Die folgenden Gennamen und Gensymbole werden für Antigen Runt-Related Transcription Factor 1 über verschiedene Spezies hinweg verwendet:

runt-related transcription factor 1 (RUNX1), runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (RUNX1T1), ch-runtB2 (LOC396152), runt-related transcription factor (runt)

Zu den weiteren Synonymen zählen:

AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1, CDR, ETO, MTG8, MTG8b, AML1T1, ZMYND2, CBFA2T1, MGC2796, RUNX1, runx1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Runt-Related Transcription Factor 1 auf:

runt-related transcription factor 1 – aml1 oncogene – OTTHUMP00000108697 – acute myeloid leukemia 1 – AML1-EVI-1 fusion protein – core-binding factor, runt domain, alpha subunit 2 – acute myelogenous leukemia 1 translocation 1 protein – eight twenty one protein – myeloid translocation gene on 8q22 – acute myelogenous leukemia 1 translocation 1, cyclin-D related – core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related – runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) – runt-related transcription factor – runt protein

Runt-Related Transcription Factor 1 erfüllt eine Reihe von Funktionen:

ATP binding – chloride ion binding – protein binding – transcription activator activity – transcription factor activity – metal ion binding – protein homodimerization activity – transcription repressor activity – zinc ion binding – DNA binding – sequence-specific DNA binding transcription factor activity

Runt-Related Transcription Factor 1 spielt in den folgenden Prozessen eine Rolle:

multicellular organismal development – positive regulation of angiogenesis – positive regulation of granulocyte differentiation – positive regulation of transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – fat cell differentiation – generation of precursor metabolites and energy – regulation of DNA binding – behavioral response to pain – central nervous system development – definitive hemopoiesis – embryonic hemopoiesis – in utero embryonic development – liver development – neuron development – response to retinoic acid – skeletal system development

Runt-Related Transcription Factor 1 ist wie folgt lokalisiert:

nucleus

Quelle: NCBI Entrez Gene, Gene Ontology