Die folgenden Gennamen und Gensymbole werden für Antigen Retinoid X Receptor, alpha über verschiedene Spezies hinweg verwendet:

retinoid X receptor, alpha (RXRA), retinoid X receptor alpha (Rxra), retinoid X receptor, alpha (rxra-A), retinoid X receptor alpha (CpipJ_CPIJ010249)

Zu den weiteren Synonymen zählen:

NR2B1, FLJ00280, FLJ00318, FLJ16020, FLJ16733, MGC102720, Nr2b1, RXRalpha1, 9530071D11Rik, rxra-A, xRXR alpha, RXRA, RXR alpha

Auf Proteinebene tauchen folgende Bezeichner für Antigen Retinoid X Receptor, alpha auf:

retinoid X receptor, alpha – retinoic acid receptor RXR-alpha – RXR alpha 1 – OTTMUSP00000012972 – OTTMUSP00000012973 – OTTMUSP00000012974 – nuclear receptor subfamily 2 group B member 1 – retinoic acid receptor – retinoid x receptor alpha – retinoid X receptor alpha protein – retinoid X receptor alpha

Retinoid X Receptor, alpha erfüllt eine Reihe von Funktionen:

ligand-regulated transcription factor activity – metal ion binding – protein binding – retinoid-X receptor activity – sequence-specific DNA binding – steroid binding – steroid hormone receptor activity – transcription coactivator activity – transcription factor activity – vitamin D receptor binding – vitamin D response element binding – zinc ion binding – DNA binding – double-stranded DNA binding – ligand-dependent nuclear receptor activity – promoter binding – receptor activity – sequence-specific DNA binding transcription factor activity – transcription regulator activity – protein heterodimerization activity

Retinoid X Receptor, alpha spielt in den folgenden Prozessen eine Rolle:

cardiac muscle cell proliferation – cholesterol metabolic process – interspecies interaction between organisms – negative regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – response to retinoic acid – retinoic acid receptor signaling pathway – ventricular cardiac muscle cell differentiation – ventricular cardiac muscle morphogenesis – vitamin metabolic process – heart development – negative regulation of cell proliferation – positive regulation of apoptosis – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of transcription – regulation of branching involved in prostate gland morphogenesis – regulation of transcription – regulation of transcription from RNA polymerase II promoter – response to glucocorticoid stimulus – secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development – signal transduction – transcription – ventricular cardiac muscle tissue morphogenesis – aging – axon regeneration – cellular response to insulin stimulus – female pregnancy – inflammatory response – liver development – midgut development – placenta development – response to ethanol – response to nutrient – response to organic cyclic substance – response to selenium ion – response to vitamin A – response to vitamin D

Retinoid X Receptor, alpha ist wie folgt lokalisiert:

nucleus – axon

Quelle: NCBI Entrez Gene, Gene Ontology