Die folgenden Gennamen und Gensymbole werden für Antigen Retinoblastoma-Associated Protein über verschiedene Spezies hinweg verwendet:

retinoblastoma 1 (RB1)

Zu den weiteren Synonymen zählen:

RB, pRb, OSRC, pp110, p105-Rb

Auf Proteinebene tauchen folgende Bezeichner für Antigen Retinoblastoma-Associated Protein auf:

retinoblastoma 1 – retinoblastoma-associated protein – retinoblastoma suspectibility protein

Retinoblastoma-Associated Protein erfüllt eine Reihe von Funktionen:

androgen receptor binding – kinase binding – phosphoprotein binding – transcription coactivator activity – transcription factor activity – transcription factor binding – transcription repressor activity – ubiquitin protein ligase binding

Retinoblastoma-Associated Protein spielt in den folgenden Prozessen eine Rolle:

G1 phase – M phase – androgen receptor signaling pathway – cell cycle arrest – cell cycle checkpoint – cell division – chromatin remodeling – enucleate erythrocyte differentiation – interspecies interaction between organisms – myoblast differentiation – negative regulation of S phase of mitotic cell cycle – negative regulation of cell cycle – negative regulation of cell growth – negative regulation of cell proliferation – negative regulation of protein kinase activity – negative regulation of transcription from RNA polymerase II promoter – positive regulation of macrophage differentiation – positive regulation of transcription from RNA polymerase II promoter – regulation of lipid kinase activity – regulation of transcription of G1/S-phase of mitotic cell cycle – striated muscle cell differentiation

Retinoblastoma-Associated Protein ist wie folgt lokalisiert:

PML body – Rb-E2F complex – SWI/SNF complex – chromatin – nucleoplasm – nucleus – spindle

Quelle: NCBI Entrez Gene, Gene Ontology