Die folgenden Gennamen und Gensymbole werden für Antigen RAD18 Homolog (S. Cerevisiae) über verschiedene Spezies hinweg verwendet:

RAD18 homolog (S. cerevisiae) (RAD18), RAD18 homolog (S. cerevisiae) (Rad18), RAD18 homolog (S. cerevisiae) (rad18), similar to postreplication repair protein hRAD18p (RAD18), E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair (RAD18), hypothetical protein (RAD18), DNA repair protein and ATPase (RAD18), C3HC4-type zinc finger-containing protein (rad18)

Zu den weiteren Synonymen zählen:

RNF73, Rad18sc, 2810024C04Rik, MGC156682, MGC55577, zgc:55577, RAD18, MGC134015, DKFZp469H0810

Auf Proteinebene tauchen folgende Bezeichner für Antigen RAD18 Homolog (S. Cerevisiae) auf:

postreplication repair protein hRAD18p – RAD18, S. cerevisiae, homolog – RAD18 homolog – OTTMUSP00000018917 – post-replication repair protein RAD18SC – RAD18 homolog (S. cerevisiae) – similar to postreplication repair protein hRAD18p – E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair – Rad18p – hypothetical protein – DNA repair protein and ATPase – C3HC4-type zinc finger-containing protein – SAP DNA-binding domain-containing protein – RAD18-like protein – E3 ubiquitin-protein ligase RAD18-like – e3 ubiquitin-protein ligase RAD18-like

RAD18 Homolog (S. Cerevisiae) erfüllt eine Reihe von Funktionen:

Y-form DNA binding – damaged DNA binding – ligase activity – metal ion binding – protein binding – ubiquitin protein ligase binding – zinc ion binding – DNA binding – nucleic acid binding – molecular_function – single-stranded DNA binding – single-stranded DNA-dependent ATPase activity – ubiquitin-protein ligase activity – DNA-dependent ATPase activity

RAD18 Homolog (S. Cerevisiae) spielt in den folgenden Prozessen eine Rolle:

DNA repair – modification-dependent protein catabolic process – response to DNA damage stimulus – cellular response to DNA damage stimulus – negative regulation of DNA recombination – response to UV – spermatogenesis – biological_process – DNA catabolic process – error-free postreplication DNA repair – error-free translesion synthesis – error-prone translesion synthesis – protein monoubiquitination – protein ubiquitination

RAD18 Homolog (S. Cerevisiae) ist wie folgt lokalisiert:

nucleus – replication fork – XY body – chromatin – cellular_component – nuclear chromatin

Quelle: NCBI Entrez Gene, Gene Ontology