Die folgenden Gennamen und Gensymbole werden für Antigen RAD17 Homolog (S. Pombe) über verschiedene Spezies hinweg verwendet:

RAD17 homolog (S. pombe) (RAD17), RAD1 homolog (S. pombe) (Rad1), RAD1 homolog (S. pombe) (rad1), RAD1 homolog (S. pombe) (RAD1), RAD1 homolog (RAD1), RAD17 homolog (S. pombe) (rad17), Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins (RAD17)

Zu den weiteren Synonymen zählen:

CCYC, R24L, RAD24, HRAD17, RAD17SP, FLJ41520, MGC77779, zgc:56502, zgc:77779, RAD1, rad1, RAD17, DKFZp459H1127, zgc:91969, MGC140462

Auf Proteinebene tauchen folgende Bezeichner für Antigen RAD17 Homolog (S. Pombe) auf:

RAD17 homolog – RAD1 homolog – OTTHUMP00000125192 – Rad17-like protein – RF-C activator 1 homolog – cell cycle checkpoint protein (RAD17) – RAD1 homolog (S. pombe) – RAD17 homolog (S. pombe) – Cell cycle checkpoint protein RAD1 – cell cycle checkpoint protein RAD17-like – cell cycle checkpoint protein RAD17 – Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins – Rad17p – Cell cycle checkpoint protein RAD17

RAD17 Homolog (S. Pombe) erfüllt eine Reihe von Funktionen:

ATP binding – nucleoside-triphosphatase activity – nucleotide binding – protein binding – 3'-5' exonuclease activity – damaged DNA binding – exodeoxyribonuclease III activity – DNA binding – double-stranded DNA binding – exonuclease activity – hydrolase activity – nuclease activity

RAD17 Homolog (S. Pombe) spielt in den folgenden Prozessen eine Rolle:

DNA damage checkpoint – DNA repair – DNA replication checkpoint – cell cycle – mitotic cell cycle checkpoint – negative regulation of DNA replication – regulation of phosphorylation – response to DNA damage stimulus – DNA replication – double-strand break repair – reciprocal meiotic recombination – regulation of DNA metabolic process – regulation of cell cycle

RAD17 Homolog (S. Pombe) ist wie folgt lokalisiert:

cytoplasm – nucleolus – nucleus – checkpoint clamp complex

Quelle: NCBI Entrez Gene, Gene Ontology