Die folgenden Gennamen und Gensymbole werden für Antigen R-Spondin 3 über verschiedene Spezies hinweg verwendet:

N-acetyltransferase 2 (arylamine N-acetyltransferase) (NAT2), ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4), ADAM metallopeptidase with thrombospondin type 1 motif, 3 (ADAMTS3), ADAM metallopeptidase with thrombospondin type 1 motif, 2 (ADAMTS2), ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13), ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) (Adamts5), ADAM metallopeptidase with thrombospondin type 1 motif, 4 (Adamts4), R-spondin 3 homolog (Xenopus laevis) (RSPO3), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9 (Adamts9), ADAM metallopeptidase with thrombospondin type 1 motif, 19 (ADAMTS19), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19 (Adamts19), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 (Adamts4), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 (Adamts13), ADAM metallopeptidase with thrombospondin type 1 motif, 5 (Adamts5), ADAM metallopeptidase with thrombospondin type 1 motif, 19 (Adamts19), ADAM metallopeptidase with thrombospondin type 1 motif, 13 (Adamts13), ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) (ADAMTS5), R-spondin 3 (rspo3)

Zu den weiteren Synonymen zählen:

AAC2, PNAT, ADMP-1, ADAMTS-2, ADAMTS-4, KIAA0688, KIAA0366, NPI, PCINP, PCPNI, hPCPNI, ADAM-TS2, ADAMTS-3, TTP, VWFCP, C9orf8, vWF-CP, FLJ42993, MGC118899, MGC118900, DKFZp434C2322, ADMP-2, ADAMTS11, FLJ36738, ASMP-2, ADAMTS1, ADAM-TS5, AI481094, 9530092O11Rik, PWTSR, THSD2, CRISTIN1, FLJ14440, AW743315, 1810011L16Rik, 8430403M15Rik, E030027K14Rik, FLJ16042, AU015154, 4831407I23Rik, D230034E10Rik, ADAM-TS4, mKIAA0688, 3830423K05, Gm710, ADAMTS5, ADAMTS4, ADAMTS13, pwtsr, thsd2, cristin1, ADAMTS-11

Auf Proteinebene tauchen folgende Bezeichner für Antigen R-Spondin 3 auf:

N-acetyltransferase 2 – arylamide acetylase 2 – ADAM metallopeptidase with thrombospondin type 1 motif, 4 – aggrecanase-1 – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4 – ADAM metallopeptidase with thrombospondin type 1 motif, 3 – zinc metalloendopeptidase – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3 – ADAM metallopeptidase with thrombospondin type 1 motif, 2 – procollagen I N-proteinase – procollagen N-endopeptidase – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2 – ADAM metallopeptidase with thrombospondin type 1 motif, 13 – vWF-cleaving protease – von Willebrand factor-cleaving protease – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13 – ADAM metallopeptidase with thrombospondin type 1 motif, 5 – aggrecanase-2 – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) – implantin – ADAMTS-4 – Aggrecanase – a disintegrin and metallopeptidase with thrombospondin motifs 4 – a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 – R-spondin 3 – thrombospondin-like – thrombospondin, type I, domain containing 2 – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9 – ADAM metallopeptidase with thrombospondin type 1 motif, 19 – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 19 – A disintegrin and metalloproteinase with thrombospondin motifs 19 – ADAM-TS19 – ADAMTS-19 – ADAM-TS 19 – OTTMUSP00000012637 – ADAMTS13 isoform IAP-b – vWF-CP mRNA for von Willebrand factor-cleaving – ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) – a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) – a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19 – a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 – ADAM metallopeptidase with thrombospondin type 1 motif, 19-like

R-Spondin 3 erfüllt eine Reihe von Funktionen:

acetyltransferase activity – arylamine N-acetyltransferase activity – transferase activity – metal ion binding – metalloendopeptidase activity – peptidase activity – protease binding – zinc ion binding – heparin binding – calcium ion binding – integrin binding – protein binding – hydrolase activity – metallopeptidase activity – endopeptidase activity

R-Spondin 3 spielt in den folgenden Prozessen eine Rolle:

metabolic process – proteolysis – skeletal system development – collagen catabolic process – collagen fibril organization – protein maturation by peptide bond cleavage – cell-matrix adhesion – glycoprotein metabolic process – integrin-mediated signaling pathway – peptide catabolic process – platelet activation – protein processing – glycoprotein catabolic process – Wnt receptor signaling pathway – response to stimulus – positive regulation of melanocyte differentiation – regulation of developmental pigmentation – blood coagulation – hemostasis – response to chemical stimulus

R-Spondin 3 ist wie folgt lokalisiert:

cytoplasm – cytosol – extracellular region – extracellular space – proteinaceous extracellular matrix – cell surface – extracellular matrix – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology