Die folgenden Gennamen und Gensymbole werden für Antigen Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 über verschiedene Spezies hinweg verwendet:

purinergic receptor P2X, ligand-gated ion channel, 7 (P2RX7), purinergic receptor P2X, ligand-gated ion channel, 7 (p2rx7)

Zu den weiteren Synonymen zählen:

P2X7, MGC20089, P2RX7, p2xr7

Auf Proteinebene tauchen folgende Bezeichner für Antigen Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 auf:

purinergic receptor P2X7 – ATP receptor – P2Z receptor – P2X7 receptor – P2X purinoceptor 7 – purinergic receptor P2X, ligand-gated ion channel, 7 – p2X purinoceptor 7-like

Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 erfüllt eine Reihe von Funktionen:

ATP binding – ATP-gated cation channel activity – ion channel activity – lipopolysaccharide binding – protein heterodimerization activity – protein homodimerization activity – purinergic nucleotide receptor activity – receptor activity – receptor binding – channel activity – protein binding

Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 spielt in den folgenden Prozessen eine Rolle:

bleb formation – cell surface receptor linked signal transduction – ion transport – membrane depolarization – negative regulation of MAPKKK cascade – negative regulation of bone resorption – pore complex assembly – positive regulation of bone mineralization – positive regulation of calcium ion transport into cytosol – positive regulation of cytolysis – positive regulation of cytoskeleton organization – positive regulation of interleukin-1 beta secretion – regulation of apoptosis – regulation of killing of cells of another organism – regulation of sodium ion transport – response to ATP – sensory perception of pain – NAD transport – T cell homeostasis – T cell proliferation – activation of MAPK activity – calcium ion transport – cation transport – cell morphogenesis – cell volume homeostasis – cellular response to extracellular stimulus – ceramide biosynthetic process – collagen metabolic process – cytolysis – defense response to Gram-positive bacterium – gene expression – homeostasis of number of cells within a tissue – inflammatory response – membrane budding – membrane protein ectodomain proteolysis – mitochondrion organization – multicellular organismal protein catabolic process – oxygen and reactive oxygen species metabolic process – phagolysosome formation – phospholipid transfer to membrane – phospholipid translocation – plasma membrane organization – positive regulation of MAPKKK cascade – positive regulation of T cell mediated cytotoxicity – positive regulation of apoptosis – positive regulation of catalytic activity – positive regulation of cytokine secretion – positive regulation of gamma-aminobutyric acid secretion – positive regulation of glutamate secretion – positive regulation of interleukin-1 alpha secretion – positive regulation of interleukin-1 beta production – positive regulation of interleukin-6 production – positive regulation of mitochondrial depolarization – positive regulation of prostaglandin secretion – positive regulation of protein amino acid phosphorylation – protein oligomerization – protein processing – release of sequestered calcium ion into cytosol – response to bacterium – response to calcium ion – response to drug – response to electrical stimulus – response to fluid shear stress – response to lipopolysaccharide – response to mechanical stimulus – response to organic cyclic substance – response to protein stimulus – response to zinc ion – skeletal system morphogenesis – synaptic vesicle exocytosis – transport

Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 ist wie folgt lokalisiert:

bleb – cytoplasm – integral to plasma membrane – plasma membrane – cell soma – cell-cell junction – external side of plasma membrane – neuromuscular junction – synaptosome – integral to membrane – membrane

Quelle: NCBI Entrez Gene, Gene Ontology