Die folgenden Gennamen und Gensymbole werden für Antigen Purinergic Receptor P2X, Ligand Gated Ion Channel 2 über verschiedene Spezies hinweg verwendet:

purinergic receptor P2X, ligand-gated ion channel, 2 (P2RX2), purinergic receptor P2X, ligand-gated ion channel, 2 (P2rx2), purinergic receptor P2X, ligand-gated ion channel, 2 (p2rx2)

Zu den weiteren Synonymen zählen:

P2X2, MGC129601, P2x2, P2X2a, MGC129148, MGC129149, p2xr2, P2RX2

Auf Proteinebene tauchen folgende Bezeichner für Antigen Purinergic Receptor P2X, Ligand Gated Ion Channel 2 auf:

purinergic receptor P2X2 – ATP receptor – P2X purinoceptor 2 – P2X Receptor, subunit 2 – purinergic receptor P2X, ligand-gated ion channel, 2 – p2X purinoceptor 2-like

Purinergic Receptor P2X, Ligand Gated Ion Channel 2 erfüllt eine Reihe von Funktionen:

ATP binding – ATP-gated cation channel activity – ligand-gated ion channel activity – protein heterodimerization activity – protein homodimerization activity – purinergic nucleotide receptor activity – receptor activity – cadmium ion binding – cobalt ion binding – copper ion binding – drug binding – extracellular ATP-gated cation channel activity – identical protein binding – mercury ion binding – nickel ion binding – phosphoinositide binding – protein binding – zinc ion binding – ion channel activity

Purinergic Receptor P2X, Ligand Gated Ion Channel 2 spielt in den folgenden Prozessen eine Rolle:

ion transport – positive regulation of calcium ion transport into cytosol – positive regulation of calcium-mediated signaling – behavioral response to pain – cation transport – detection of hypoxic conditions in blood by carotid body chemoreceptor signaling – ion transmembrane transport – neuromuscular junction development – neuromuscular synaptic transmission – peristalsis – protein heterooligomerization – protein homooligomerization – regulation of action potential in neuron – response to ATP – response to carbohydrate stimulus – response to hypoxia – response to organic substance – sensory perception of taste – skeletal muscle fiber development – synaptic transmission – urinary bladder smooth muscle contraction – transport

Purinergic Receptor P2X, Ligand Gated Ion Channel 2 ist wie folgt lokalisiert:

integral to membrane – membrane – dendritic spine – intracellular part – membrane fraction – neuronal cell body – plasma membrane – postsynaptic density – presynaptic membrane – terminal button

Quelle: NCBI Entrez Gene, Gene Ontology