Die folgenden Gennamen und Gensymbole werden für Antigen Protein tyrosine Phosphatase, Receptor Type, C über verschiedene Spezies hinweg verwendet:

protein tyrosine phosphatase, receptor type, C (PTPRC), protein tyrosine phosphatase, receptor type, C (Ptprc), protein tyrosine phosphatase, receptor type, C (ptprc)

Zu den weiteren Synonymen zählen:

LCA, LY5, B220, CD45, T200, CD45R, GP180, Lca, RT7, L-CA, PTPRC, si:dkeyp-47c5.1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Protein tyrosine Phosphatase, Receptor Type, C auf:

protein tyrosine phosphatase, receptor type, C – CD45 antigen – glycoprotein – T200 glycoprotein – leukocyte-common antigen – T200 leukocyte common antigen – protein tyrosine phosphatase, receptor type, c polypeptide – receptor-type tyrosine-protein phosphatase C – leucocyte common antigen – leukocyte common antigen A – leukocyte common antigen B – Protein tyrosine phosphatase, receptor-type, c polypeptide – leukocyte common antigen, CD45 – cd45 – leukocyte common antigen – receptor-type tyrosine-protein phosphatase C-like

Protein tyrosine Phosphatase, Receptor Type, C erfüllt eine Reihe von Funktionen:

hydrolase activity – protein binding – protein kinase binding – transmembrane receptor protein tyrosine phosphatase activity – heparan sulfate proteoglycan binding – heparin binding – protein kinase regulator activity – protein tyrosine phosphatase activity – phosphatase activity – receptor activity

Protein tyrosine Phosphatase, Receptor Type, C spielt in den folgenden Prozessen eine Rolle:

B cell receptor signaling pathway – T cell differentiation – T cell receptor signaling pathway – cell surface receptor linked signal transduction – defense response to virus – immunoglobulin biosynthetic process – negative regulation of T cell mediated cytotoxicity – negative regulation of cytokine-mediated signaling pathway – negative regulation of protein kinase activity – positive regulation of B cell proliferation – positive regulation of T cell proliferation – positive regulation of antigen receptor-mediated signaling pathway – positive regulation of protein kinase activity – protein amino acid dephosphorylation – regulation of S phase – regulation of cell cycle – release of sequestered calcium ion into cytosol – B cell differentiation – B cell proliferation – T cell proliferation – activation of MAPK activity – dephosphorylation – heterotypic cell-cell adhesion – leukocyte cell-cell adhesion – negative regulation of peptidyl-tyrosine phosphorylation – negative regulation of protein amino acid autophosphorylation – negative thymic T cell selection – positive regulation of MAPKKK cascade – positive regulation of T cell differentiation – positive regulation of T cell mediated cytotoxicity – positive regulation of T cell mediated immunity – positive regulation of alpha-beta T cell proliferation – positive regulation of apoptosis – positive regulation of gamma-delta T cell differentiation – positive regulation of humoral immune response mediated by circulating immunoglobulin – positive regulation of isotype switching to IgG isotypes – positive thymic T cell selection – regulation of B cell differentiation – regulation of B cell receptor signaling pathway – regulation of apoptosis – regulation of humoral immune response mediated by circulating immunoglobulin – response to gamma radiation

Protein tyrosine Phosphatase, Receptor Type, C ist wie folgt lokalisiert:

focal adhesion – integral to plasma membrane – plasma membrane – cell surface – external side of plasma membrane – integral to membrane – internal side of plasma membrane – membrane raft

Quelle: NCBI Entrez Gene, Gene Ontology