Die folgenden Gennamen und Gensymbole werden für Antigen Protein Inhibitor of Activated STAT, 2 über verschiedene Spezies hinweg verwendet:

protein inhibitor of activated STAT, 2 (PIAS2), protein inhibitor of activated STAT, 2 (Pias2), protein inhibitor of activated STAT, 2 (pias2)

Zu den weiteren Synonymen zählen:

miz, MIZ1, SIZ2, PIASX, ZMIZ4, MGC102682, PIASX-BETA, PIASX-ALPHA, Miz1, MGC83751, PIAS2, wu:fi05f09

Auf Proteinebene tauchen folgende Bezeichner für Antigen Protein Inhibitor of Activated STAT, 2 auf:

protein inhibitor of activated STAT X – Msx-interacting-zinc finger – zinc finger, MIZ-type containing 4 – E3 SUMO-protein ligase PIAS2 – DIP – ARIP3 – DAB2-interacting protein – msx-interacting-zinc finger protein – protein inhibitor of activated STAT x – androgen receptor-interacting protein 3 – protein inhibitor of activated STAT, 2 – fi05f09 – E3 SUMO-protein ligase PIAS2-like – e3 SUMO-protein ligase PIAS2-like

Protein Inhibitor of Activated STAT, 2 erfüllt eine Reihe von Funktionen:

DNA binding – SUMO ligase activity – androgen receptor binding – metal ion binding – protein binding – transcription coactivator activity – zinc ion binding – estrogen receptor binding – glucocorticoid receptor binding – nucleic acid binding – RNA polymerase II transcription factor activity – transcription activator activity

Protein Inhibitor of Activated STAT, 2 spielt in den folgenden Prozessen eine Rolle:

androgen receptor signaling pathway – modification-dependent protein catabolic process – positive regulation of transcription, DNA-dependent – regulation of transcription – negative regulation of androgen receptor signaling pathway – positive regulation of dendrite morphogenesis – positive regulation of transcription – protein sumoylation – regulation of androgen receptor signaling pathway – response to organic substance – response to testosterone stimulus – spermatogenesis – positive regulation of gene-specific transcription from RNA polymerase II promoter – regulation of osteoblast differentiation – transcription, DNA-dependent

Protein Inhibitor of Activated STAT, 2 ist wie folgt lokalisiert:

nuclear speck – nucleus – nuclear body

Quelle: NCBI Entrez Gene, Gene Ontology