Die folgenden Gennamen und Gensymbole werden für Antigen Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) über verschiedene Spezies hinweg verwendet:

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (PTGS1), prostaglandin-endoperoxide synthase 1 (Ptgs1), prostaglandin-endoperoxide synthase 1 (PTGS1), cyclooxygenase-1 (COX-1), cyclooxygenase 1 (cox1), cyclooxygenase-1 (cox-1), prostaglandin-endoperoxide synthase 1 (ptgs1)

Zu den weiteren Synonymen zählen:

COX1, COX3, PHS1, PCOX1, PGHS1, PTGHS, PGG/HS, PGHS-1, Cox-1, Cox-3, Pghs1, Cox1, Cox3, PTGS1, COX-1, Ptgs1, cox1, cox-1, zCOX-1, COX-3

Auf Proteinebene tauchen folgende Bezeichner für Antigen Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) auf:

prostaglandin-endoperoxide synthase 1 – prostaglandin G/H synthase and cyclooxygenase – prostaglandin G/H synthase 1 – PHS 1 – PGHS-1 – PGH synthase 1 – cyclooxygenase 1 – cyclooxygenase-1 – OTTMUSP00000013094 – prostaglandin H2 synthase 1 – COX-1 – cyclooxygenase 3 – Cox-1 – Cox-1b – cyclooxygenase – prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) – Prostaglandin G/H synthase 1 – prostaglandin endoperoxide synthase

Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) erfüllt eine Reihe von Funktionen:

heme binding – lipid binding – metal ion binding – oxidoreductase activity – oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen – peroxidase activity – prostaglandin-endoperoxide synthase activity

Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) spielt in den folgenden Prozessen eine Rolle:

fatty acid biosynthetic process – oxidation reduction – prostaglandin biosynthetic process – regulation of blood pressure – regulation of cell proliferation – response to oxidative stress – keratinocyte differentiation – lipid biosynthetic process – negative regulation of epinephrine secretion – negative regulation of norepinephrine secretion – positive regulation of smooth muscle contraction – positive regulation of vasoconstriction – prostaglandin metabolic process – aging – cyclooxygenase pathway – response to corticosterone stimulus – response to organic nitrogen – kidney development – oxidation-reduction process – response to chemical stimulus – vasculogenesis

Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) ist wie folgt lokalisiert:

Golgi apparatus – cytoplasm – endoplasmic reticulum – extrinsic to membrane – microsome – nucleus – plasma membrane – membrane – nuclear envelope – endoplasmic reticulum membrane

Quelle: NCBI Entrez Gene, Gene Ontology