Die folgenden Gennamen und Gensymbole werden für Antigen Proprotein Convertase Subtilisin/kexin Type 1 über verschiedene Spezies hinweg verwendet:

proprotein convertase subtilisin/kexin type 1 (PCSK1), proprotein convertase subtilisin/kexin type 1 (Pcsk1), proprotein convertase subtilisin/kexin type 1 (pcsk1), prohormone convertase 1 (PC1B), prohormone convertase 1 (LOC100534403), prohormone convertase 1 (LOC100534404)

Zu den weiteren Synonymen zählen:

PC1, PC3, NEC1, SPC3, BMIQ12, Nec1, Nec-1, Phpp-1, MGC124320, MGC124321, BDP

Auf Proteinebene tauchen folgende Bezeichner für Antigen Proprotein Convertase Subtilisin/kexin Type 1 auf:

proprotein convertase subtilisin/kexin type 1 – prohormone convertase 1 – prohormone convertase 3 – proprotein convertase 1 – neuroendocrine convertase 1 – NEC 1 – furin homolog – OTTMUSP00000031918 – prohormone convertase 1/3 – propeptide-processing protease – Protein convertase subtilisin / kexin type I – Protein convertase subtilisin / kexin, type I

Proprotein Convertase Subtilisin/kexin Type 1 erfüllt eine Reihe von Funktionen:

calcium ion binding – peptidase activity – serine-type endopeptidase activity – chaperone binding – endopeptidase activity – hydrolase activity – insulin binding – protein complex binding – serine-type peptidase activity

Proprotein Convertase Subtilisin/kexin Type 1 spielt in den folgenden Prozessen eine Rolle:

cell-cell signaling – metabolic process – peptide biosynthetic process – peptide hormone processing – protein maturation by peptide bond cleavage – proteolysis – positive regulation of protein secretion – protein autoprocessing – embryo development – neurogenesis – pancreas development – pituitary gland development – response to axon injury – response to calcium ion – response to chlorate – response to drug – response to fatty acid – response to glucocorticoid stimulus – response to glucose stimulus – response to inorganic substance – response to interleukin-1 – response to lipopolysaccharide – response to morphine – response to nutrient levels – response to organic cyclic substance – response to peptide hormone stimulus – response to protein stimulus

Proprotein Convertase Subtilisin/kexin Type 1 ist wie folgt lokalisiert:

cytoplasmic vesicle – extracellular space – secretory granule – axon terminus – dendrite – neuron projection – neuronal cell body – perinuclear region of cytoplasm – rough endoplasmic reticulum – stored secretory granule – trans-Golgi network – transport vesicle

Quelle: NCBI Entrez Gene, Gene Ontology