Die folgenden Gennamen und Gensymbole werden für Antigen Progesterone Receptor über verschiedene Spezies hinweg verwendet:

progesterone receptor (PGR), progesterone receptor (Pgr), progesterone receptor (pgr-A), progesterone receptor (LOC443444), progesterone receptor (pgr), progesterone receptor (PR), progesterone receptor (pr)

Zu den weiteren Synonymen zählen:

PR, NR3C3, PR-A, PR-B, BB114106, 9930019P03Rik, ENSMUSG00000074510, PGR, pgr-A, XPR-1, LOC443444, pg, pr, gb:dq017620

Auf Proteinebene tauchen folgende Bezeichner für Antigen Progesterone Receptor auf:

progesterone receptor – OTTMUSP00000026522 – OTTMUSP00000026523 – nuclear receptor subfamily 3 group C member 3 – PR – p4 receptor – Nuclear receptor subfamily 3 group C member 3 – NR3C3

Progesterone Receptor erfüllt eine Reihe von Funktionen:

metal ion binding – protein N-terminus binding – sequence-specific DNA binding – steroid binding – steroid hormone receptor activity – transcription factor activity – zinc ion binding – DNA binding – hormone binding – ligand-dependent nuclear receptor activity – lipid binding – protein binding – receptor activity – sequence-specific DNA binding transcription factor activity – transcription activator activity – transcription regulator activity – receptor binding

Progesterone Receptor spielt in den folgenden Prozessen eine Rolle:

cell-cell signaling – epithelial cell maturation – mammary gland development – ovulation from ovarian follicle – progesterone receptor signaling pathway – regulation of epithelial cell proliferation – regulation of transcription, DNA-dependent – signal transduction – positive regulation of transcription, DNA-dependent – regulation of transcription – steroid hormone mediated signaling pathway – tertiary branching involved in mammary gland duct morphogenesis – transcription – negative regulation of transcription, DNA-dependent

Progesterone Receptor ist wie folgt lokalisiert:

cytoplasm – nucleus – neuron projection – intracellular membrane-bounded organelle – soluble fraction

Quelle: NCBI Entrez Gene, Gene Ontology