Die folgenden Gennamen und Gensymbole werden für Antigen Prion Protein über verschiedene Spezies hinweg verwendet:

prion protein (PRNP), prion protein (Prnp), prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) (PRNP), prion protein (prnp), prion protein (PRP)

Zu den weiteren Synonymen zählen:

CJD, GSS, PrP, ASCR, PRIP, PrPc, CD230, prion, MGC26679, PrP27-30, PrP33-35C, Prn, MGC140197, prp, Prn-p, cjd, prp(c), MGC84114, PRNP, PRP, Prp, SIP, PRPC, DKFZp459A016

Auf Proteinebene tauchen folgende Bezeichner für Antigen Prion Protein auf:

prion protein – p27-30 – CD230 antigen – prion protein PrP – major prion protein – prion-related protein – prion protein, PrP – Prion protein, structural – prion protein precursor PrP – major scrapie-associated fibril protein 1 – prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) – prion-like protein – prion-like-protein – infectious amyloid – Major prion protein

Prion Protein erfüllt eine Reihe von Funktionen:

copper ion binding – identical protein binding – microtubule binding – metal ion binding – protein binding – tubulin binding

Prion Protein spielt in den folgenden Prozessen eine Rolle:

anti-apoptosis – cellular copper ion homeostasis – metabolic process – protein homooligomerization – response to cadmium ion – response to copper ion – response to oxidative stress – negative regulation of apoptosis – regulation of transcription, DNA-dependent – signal transduction

Prion Protein ist wie folgt lokalisiert:

Golgi apparatus – anchored to membrane – cytoplasm – endoplasmic reticulum – extrinsic to membrane – membrane raft – plasma membrane – anchored to plasma membrane – cell surface

Quelle: NCBI Entrez Gene, Gene Ontology