Die folgenden Gennamen und Gensymbole werden für Antigen Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa über verschiedene Spezies hinweg verwendet:

polymerase (RNA) II (DNA directed) polypeptide A, 220kDa (POLR2A), polymerase (RNA) II (DNA directed) polypeptide A (Polr2a), DNA-directed RNA polymerase II largest subunit (NCU02103), DNA-directed RNA polymerase II largest subunit (BBOV_I003360), DNA-directed RNA polymerase II subunit RPB1 (EDI_169920), DNA-directed RNA polymerase II subunit RPB1 (CMU_000800), DNA-directed RNA polymerase II subunit RPB1 (SJAG_01713), DNA-directed RNA polymerase II subunit RPB1 (MGYG_01527), DNA-directed RNA polymerase II largest subunit (TP03_0185), DNA-directed RNA polymerase II largest subunit (EBI_22514), DNA-directed RNA polymerase II largest subunit (CGB_E5020W), polymerase (RNA) II (DNA directed) polypeptide A, 220kDa (polr2a)

Zu den weiteren Synonymen zählen:

RPB1, RPO2, POLR2, POLRA, RPBh1, RPOL2, RpIILS, hsRPB1, hRPB220, MGC75453, Rpb1, 220kDa, Rpo2-1, 19.m02399, POLR2A

Auf Proteinebene tauchen folgende Bezeichner für Antigen Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa auf:

DNA-directed RNA polymerase II A – DNA-directed RNA polymerase II subunit A – RNA-directed RNA polymerase II subunit RPB1 – DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit – DNA-directed RNA polymerase II subunit RPB1 – RNA polymerase II 1 – RNA polymerase II subunit B1 – DNA-directed RNA polymerase III largest subunit – polymerase (RNA) II (DNA directed) polypeptide A – Polymerase (RNA II (DNA directed), large polypeptide – polymerase (RNA) II (DNA directed) polypeptide A, 220kDa – DNA-directed RNA polymerase II largest subunit – polymerase (RNA) II (DNA directed) polypeptide A (220kD) – RNA polymerase II polypeptide A

Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa erfüllt eine Reihe von Funktionen:

DNA binding – DNA-directed RNA polymerase activity – RNA-directed RNA polymerase activity – magnesium ion binding – nucleotidyltransferase activity – protein binding – protein kinase activity – transferase activity – ubiquitin protein ligase binding – zinc ion binding – metal ion binding – molecular_function

Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa spielt in den folgenden Prozessen eine Rolle:

RNA elongation from RNA polymerase II promoter – nuclear mRNA splicing, via spliceosome – regulation of transcription, DNA-dependent – transcription – transcription initiation from RNA polymerase II promoter – transcription from RNA polymerase II promoter – RNA splicing – biological_process

Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa ist wie folgt lokalisiert:

DNA-directed RNA polymerase II, core complex – nucleolus – nucleoplasm – nucleus – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology