Die folgenden Gennamen und Gensymbole werden für Antigen Polymerase (DNA Directed), epsilon über verschiedene Spezies hinweg verwendet:

polymerase (DNA directed), epsilon (POLE), polymerase (DNA directed), epsilon (Pole), DNA polymerase epsilon (DNApol-epsilon), polymerase (DNA directed), epsilon (pole), DNA polymerase epsilon (NCU04548), DNA polymerase epsilon (CpipJ_CPIJ008666), DNA polymerase epsilon (CTRG_00708), DNA polymerase epsilon (UREG_06843), DNA polymerase epsilon catalytic subunit A/1 (POLE1)

Zu den weiteren Synonymen zählen:

POLE1, FLJ21434, DKFZp434F222, BAB17608, pol-epsilon, DmelCG6768, CG6768, pole1, pole-A, si:dkeyp-98c11.2

Auf Proteinebene tauchen folgende Bezeichner für Antigen Polymerase (DNA Directed), epsilon auf:

DNA polymerase epsilon catalytic subunit A – DNA polymerase II subunit A – pol-epsilon – OTTMUSP00000032240 – DNA-directed DNA polymerase epsilon – DNA polymerase epsilon – CG6768-PA – DNApol-epsilon-PA – DNApolymarase E – polymerase (DNA directed), epsilon – DNA polymerase epsilon catalytic subunit – novel protein similar to vertebrate polymerase (DNA directed), epsilon (POLE) – DNA polymerase epsilon catalytic subunit A-like – DNA polymerase epsilon catalytic subunit A/1

Polymerase (DNA Directed), epsilon erfüllt eine Reihe von Funktionen:

DNA binding – DNA-directed DNA polymerase activity – chromatin binding – metal ion binding – nucleotide binding – nucleotidyltransferase activity – protein binding – transferase activity – zinc ion binding – nucleic acid binding – 3'-5'-exodeoxyribonuclease activity – molecular_function

Polymerase (DNA Directed), epsilon spielt in den folgenden Prozessen eine Rolle:

DNA replication – DNA synthesis involved in DNA repair – G1/S transition of mitotic cell cycle – nucleobase, nucleoside, nucleotide and nucleic acid metabolic process – nucleotide-excision repair, DNA gap filling – DNA repair – response to DNA damage stimulus – DNA-dependent DNA replication – cellular response to DNA damage stimulus – in utero embryonic development

Polymerase (DNA Directed), epsilon ist wie folgt lokalisiert:

nucleoplasm – nucleus – epsilon DNA polymerase complex – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology