Die folgenden Gennamen und Gensymbole werden für Antigen Pleckstrin Homology-Like Domain, Family A, Member 2 über verschiedene Spezies hinweg verwendet:

pleckstrin homology-like domain, family A, member 2 (PHLDA2), pleckstrin homology-like domain, family A, member 3 (PHLDA3), pleckstrin homology-like domain, family A, member 2 (Phlda2), pleckstrin homology-like domain, family A, member 2 (phlda2)

Zu den weiteren Synonymen zählen:

IPL, BRW1C, BWR1C, HLDA2, TSSC3, TIH1, MGC110459, zgc:110459, PHLDA2, MGC142673

Auf Proteinebene tauchen folgende Bezeichner für Antigen Pleckstrin Homology-Like Domain, Family A, Member 2 auf:

pleckstrin homology-like domain family A member 2 – tumor-supressing STF cDNA 3 – imprinted in placenta and liver – p17-Beckwith-Wiedemann region 1C – tumor suppressing subtransferable candidate 3 – tumor suppressing subchromosomal transferable fragment cDNA 3 – pleckstrin homology-like domain, family A, member 3 – OTTHUMP00000033920 – pleckstrin homology-like domain, family A, member 2 – imprinted in placenta and liver protein

Pleckstrin Homology-Like Domain, Family A, Member 2 erfüllt eine Reihe von Funktionen:

apoptosis – organ morphogenesis – identical protein binding – phosphatidylinositol 3-phosphate binding – phosphatidylinositol-3,4,5-trisphosphate binding – phosphatidylinositol-3,4-bisphosphate binding – phosphatidylinositol-3,5-bisphosphate binding – phosphatidylinositol-4,5-bisphosphate binding – phosphatidylinositol-5-phosphate binding – molecular_function

Pleckstrin Homology-Like Domain, Family A, Member 2 spielt in den folgenden Prozessen eine Rolle:

cytoplasm – extrinsic to membrane – membrane – DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis – anatomical structure morphogenesis – apoptosis – induction of apoptosis – negative regulation of protein kinase B signaling cascade – organ morphogenesis – biological_process

Pleckstrin Homology-Like Domain, Family A, Member 2 ist wie folgt lokalisiert:

cytoplasm – plasma membrane – membrane – extrinsic to membrane

Quelle: NCBI Entrez Gene, Gene Ontology