Die folgenden Gennamen und Gensymbole werden für Antigen Platelet-Derived Growth Factor Receptor beta über verschiedene Spezies hinweg verwendet:

platelet-derived growth factor receptor, beta polypeptide (PDGFRB), platelet-derived growth factor receptor beta (pdgfrb), platelet-derived growth factor receptor beta (LOC100342872)

Zu den weiteren Synonymen zählen:

JTK12, PDGFR, CD140B, PDGFR1, PDGFRB, pdgfrb

Auf Proteinebene tauchen folgende Bezeichner für Antigen Platelet-Derived Growth Factor Receptor beta auf:

platelet-derived growth factor receptor beta – PDGF-R-beta – soluble PDGFRb variant 1 – CD140 antigen-like family member B – beta-type platelet-derived growth factor receptor – protein tyrosin kinase – platelet-derived growth factor receptor, beta polypeptide – x

Platelet-Derived Growth Factor Receptor beta erfüllt eine Reihe von Funktionen:

ATP binding – nucleotide binding – platelet activating factor receptor activity – platelet-derived growth factor beta-receptor activity – platelet-derived growth factor binding – platelet-derived growth factor receptor binding – receptor activity – transferase activity – vascular endothelial growth factor receptor activity – kinase activity – protein binding

Platelet-Derived Growth Factor Receptor beta spielt in den folgenden Prozessen eine Rolle:

cell chemotaxis – in utero embryonic development – kidney development – nitrogen compound metabolic process – platelet-derived growth factor receptor signaling pathway – positive regulation of cell migration – positive regulation of cell proliferation – protein amino acid autophosphorylation – regulation of peptidyl-tyrosine phosphorylation – signal transduction – skeletal system morphogenesis – smooth muscle tissue development – tissue homeostasis – vascular endothelial growth factor receptor signaling pathway – protein amino acid phosphorylation

Platelet-Derived Growth Factor Receptor beta ist wie folgt lokalisiert:

integral to plasma membrane – plasma membrane – membrane

Quelle: NCBI Entrez Gene, Gene Ontology