Die folgenden Gennamen und Gensymbole werden für Antigen Platelet Derived Growth Factor AA über verschiedene Spezies hinweg verwendet:

platelet-derived growth factor alpha polypeptide (PDGFA), platelet-derived growth factor alpha a (pdgfaa), platelet-derived growth factor alpha polypeptide (pdgfa)

Zu den weiteren Synonymen zählen:

PDGF1, PDGF-A, pdgfa, zgc:100777, PDGFA, pdgf, pdgf1, pdgf-a

Auf Proteinebene tauchen folgende Bezeichner für Antigen Platelet Derived Growth Factor AA auf:

platelet-derived growth factor alpha – PDGF A-chain – platelet-derived growth factor alpha chain – platelet-derived growth factor alpha isoform 2 preproprotein – platelet-derived growth factor alpha a – platelet-derived growth factor alpha polypeptide

Platelet Derived Growth Factor AA erfüllt eine Reihe von Funktionen:

cell surface binding – collagen binding – growth factor activity – platelet-derived growth factor binding – platelet-derived growth factor receptor binding – protein heterodimerization activity – protein homodimerization activity

Platelet Derived Growth Factor AA spielt in den folgenden Prozessen eine Rolle:

cell activation – cell-cell signaling – embryonic development – negative chemotaxis – negative regulation of phosphatidylinositol biosynthetic process – negative regulation of platelet activation – platelet-derived growth factor receptor signaling pathway – positive regulation of DNA replication – positive regulation of cell division – positive regulation of cell migration – positive regulation of fibroblast proliferation – regulation of actin cytoskeleton organization – regulation of smooth muscle cell migration – wound healing – multicellular organismal development – actin cytoskeleton organization – angiogenesis – cell projection assembly – lung alveolus development – organ morphogenesis – regulation of peptidyl-tyrosine phosphorylation

Platelet Derived Growth Factor AA ist wie folgt lokalisiert:

cell surface – extracellular region – extracellular space – membrane – platelet dense granule lumen – microvillus

Quelle: NCBI Entrez Gene, Gene Ontology