Die folgenden Gennamen und Gensymbole werden für Antigen Phospholipase C, epsilon 1 über verschiedene Spezies hinweg verwendet:

phospholipase C, epsilon 1 (PLCE1), phospholipase C, epsilon 1 (Plce1), phospholipase C, epsilon 1 (plce1), phospholipase C, epsilon 1 (LOC100344504)

Zu den weiteren Synonymen zählen:

PLCE, PPLC, NPHS3, FLJ23659, KIAA1516, MGC167842, Plce, mKIAA1516, PLCepsilon, 4933403A21Rik, PLCE1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Phospholipase C, epsilon 1 auf:

phospholipase C, epsilon 1 – nephrosis type 3 – phospholipase C-epsilon-1 – pancreas-enriched phospholipase C – phosphoinositide-specific phospholipase C epsilon-1 – 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1 – PLC-epsilon-1 – phospholipase C epsilon – 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1-like

Phospholipase C, epsilon 1 erfüllt eine Reihe von Funktionen:

Ras GTPase binding – calcium ion binding – enzyme binding – guanyl-nucleotide exchange factor activity – hydrolase activity – phosphoinositide phospholipase C activity – receptor signaling protein activity – phospholipase C activity – phosphoric diester hydrolase activity – signal transducer activity

Phospholipase C, epsilon 1 spielt in den folgenden Prozessen eine Rolle:

activation of MAPK activity – activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger – activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway – calcium-mediated signaling – cell proliferation – cytoskeleton organization – diacylglycerol biosynthetic process – elevation of cytosolic calcium ion concentration – epidermal growth factor receptor signaling pathway – glomerulus development – heart development – inositol phosphate-mediated signaling – lipid catabolic process – phospholipid metabolic process – regulation of G-protein coupled receptor protein signaling pathway – regulation of Ras protein signal transduction – regulation of cell growth – regulation of protein kinase activity – regulation of smooth muscle contraction – intracellular signaling cascade – lipid metabolic process – signal transduction – small GTPase mediated signal transduction – G-protein coupled receptor protein signaling pathway – Ras protein signal transduction – glomerular basement membrane development

Phospholipase C, epsilon 1 ist wie folgt lokalisiert:

Golgi apparatus – Golgi membrane – cytoplasm – cytosol – intracellular – membrane fraction – plasma membrane – membrane – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology