Die folgenden Gennamen und Gensymbole werden für Antigen Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide über verschiedene Spezies hinweg verwendet:

phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA), Phosphoinositide-3-kinase, catalytic, alpha polypeptide (GL50803_14855), phosphoinositide-3-kinase, catalytic, alpha polypeptide (pik3ca), phosphoinositide-3-kinase, catalytic, alpha polypeptide (LOC100229768), phosphoinositide-3-kinase, catalytic, alpha polypeptide (LOC100337822), phosphoinositide-3-kinase, catalytic, alpha polypeptide (Pik3ca)

Zu den weiteren Synonymen zählen:

PI3K, MGC142161, MGC142163, p110-alpha, C-P3K, PIK3CA, pi3k, MGC116320

Auf Proteinebene tauchen folgende Bezeichner für Antigen Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide auf:

phosphoinositide-3-kinase, catalytic, alpha polypeptide – PtdIns-3-kinase p110 – PI3-kinase p110 subunit alpha – phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha – phosphatidylinositol 3-kinase, catalytic, alpha polypeptide – phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform – phosphoinositide 3-kinase catalytic subunit – Phosphoinositide-3-kinase, catalytic, alpha polypeptide

Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide erfüllt eine Reihe von Funktionen:

1-phosphatidylinositol-3-kinase activity – ATP binding – inositol or phosphatidylinositol kinase activity – insulin receptor substrate binding – nucleotide binding – phosphatidylinositol-4,5-bisphosphate 3-kinase activity – phosphotransferase activity, alcohol group as acceptor – transferase activity – binding – protein binding

Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide spielt in den folgenden Prozessen eine Rolle:

anti-apoptosis – glucose metabolic process – phosphoinositide phosphorylation – phosphoinositide-mediated signaling – protein amino acid phosphorylation – protein kinase B signaling cascade – regulation of multicellular organism growth – signal transduction – negative regulation of apoptosis

Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide ist wie folgt lokalisiert:

cytosol – lamellipodium – phosphoinositide 3-kinase complex

Quelle: NCBI Entrez Gene, Gene Ontology