Die folgenden Gennamen und Gensymbole werden für Antigen Phosphatidylinositol 3-Kinase Regulatory Subunit alpha über verschiedene Spezies hinweg verwendet:

phosphoinositide-3-kinase, regulatory subunit 1 (alpha) (PIK3R1)

Zu den weiteren Synonymen zählen:

p85, GRB1, p85-ALPHA, PIK3R1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Phosphatidylinositol 3-Kinase Regulatory Subunit alpha auf:

phosphoinositide-3-kinase, regulatory subunit 1 (alpha) – phosphatidylinositol 3-kinase, regulatory, 1 – phosphatidylinositol 3-kinase-associated p-85 alpha – phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) – phosphatidylinositol 3-kinase regulatory subunit alpha

Phosphatidylinositol 3-Kinase Regulatory Subunit alpha erfüllt eine Reihe von Funktionen:

ErbB-3 class receptor binding – insulin binding – insulin receptor binding – insulin receptor substrate binding – insulin-like growth factor receptor binding – phosphatidylinositol binding – phosphoinositide 3-kinase regulator activity – protein phosphatase binding

Phosphatidylinositol 3-Kinase Regulatory Subunit alpha spielt in den folgenden Prozessen eine Rolle:

B cell differentiation – growth hormone receptor signaling pathway – insulin receptor signaling pathway – insulin-like growth factor receptor signaling pathway – interspecies interaction between organisms – negative regulation of apoptosis – negative regulation of cell-matrix adhesion – negative regulation of osteoclast differentiation – phosphoinositide 3-kinase cascade – phosphoinositide phosphorylation – positive regulation of cell migration – positive regulation of glucose import – protein amino acid phosphorylation – regulation of establishment of protein localization – signal transduction

Phosphatidylinositol 3-Kinase Regulatory Subunit alpha ist wie folgt lokalisiert:

1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex – cytosol – intracellular – membrane

Quelle: NCBI Entrez Gene, Gene Ontology