Die folgenden Gennamen und Gensymbole werden für Antigen Peroxisome Proliferator-Activated Receptor gamma über verschiedene Spezies hinweg verwendet:

peroxisome proliferator-activated receptor gamma (PPARG), peroxisome proliferator activated receptor gamma (Pparg), peroxisome proliferator-activated receptor gamma 1-b (PPARGAMMA)

Zu den weiteren Synonymen zählen:

MGC139055, PPARG, GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma, Nr1c3, PPAR-gamma, PPARgamma2, PPAR-gamma2, PPARGAMMA

Auf Proteinebene tauchen folgende Bezeichner für Antigen Peroxisome Proliferator-Activated Receptor gamma auf:

peroxisome proliferator-activated receptor gamma – PPAR-gamma – nuclear receptor subfamily 1 group C member 3 – peroxisome proliferative activated receptor, gamma – peroxisome proliferative activated receptor gamma – peroxisome proliferator activator receptor gamma – PPAR gamma – OTTHUMP00000185030 – OTTHUMP00000185033 – peroxisome proliferator-activated receptor gamma 1 – peroxisome proliferator activated receptor gamma 2 – peroxisome proliferator activated receptor gamma 4 – peroxisome proliferator-activated receptor gamma 1-b – peroxisome proliferator-activated receptor gamma 1-a

Peroxisome Proliferator-Activated Receptor gamma erfüllt eine Reihe von Funktionen:

DNA binding – arachidonic acid binding – chromatin binding – drug binding – metal ion binding – retinoid X receptor binding – sequence-specific DNA binding – sequence-specific DNA binding transcription factor activity – specific transcriptional repressor activity – steroid hormone receptor activity – transcription activator activity – transcription activator binding – transcription repressor activity – zinc ion binding – prostaglandin receptor activity – protein heterodimerization activity – transcription factor activity – ligand-dependent nuclear receptor activity – promoter binding – protein binding – receptor activity

Peroxisome Proliferator-Activated Receptor gamma spielt in den folgenden Prozessen eine Rolle:

activation of caspase activity – brown fat cell differentiation – cell fate commitment – cell maturation – cellular response to insulin stimulus – epithelial cell differentiation – glucose homeostasis – induction of apoptosis – lipoprotein transport – long-chain fatty acid transport – low-density lipoprotein receptor biosynthetic process – monocyte differentiation – negative regulation of cell proliferation – negative regulation of cholesterol storage – negative regulation of cytokine production – negative regulation of gene-specific transcription from RNA polymerase II promoter – negative regulation of receptor biosynthetic process – negative regulation of sequestering of triglyceride – negative regulation of transcription, DNA-dependent – placenta development – positive regulation of fat cell differentiation – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of transcription – positive regulation of transcription factor activity – regulation of blood pressure – regulation of fat cell differentiation – regulation of transcription – response to lipid – response to low-density lipoprotein stimulus – signal transduction – white fat cell differentiation – innate immune response – lipid homeostasis – lipid metabolic process – negative regulation of macrophage derived foam cell differentiation – response to low density lipoprotein stimulus – response to nutrient – cellular response to lithium ion – cellular response to organic cyclic substance – fat cell differentiation – fatty acid oxidation – inflammatory response – negative regulation of acute inflammatory response – negative regulation of cell growth – negative regulation of telomerase activity – negative regulation of transcription from RNA polymerase II promoter – positive regulation of fatty acid oxidation – positive regulation of oligodendrocyte differentiation – positive regulation of transcription from RNA polymerase II promoter – regulation of lipid metabolic process – regulation of transcription, DNA-dependent – transcription

Peroxisome Proliferator-Activated Receptor gamma ist wie folgt lokalisiert:

cytosol – nucleus – transcriptional repressor complex

Quelle: NCBI Entrez Gene, Gene Ontology