Die folgenden Gennamen und Gensymbole werden für Antigen Peroxisome Proliferator-Activated Receptor delta über verschiedene Spezies hinweg verwendet:

peroxisome proliferator activator receptor delta (Ppard), peroxisome proliferator-activated receptor delta (PPARD), peroxisome proliferator activated receptor beta (ppard), peroxisome proliferator-activated receptor delta (ppard)

Zu den weiteren Synonymen zählen:

NUC1, NUC-1, Nr1c2, Pparb, PPAR[b], Pparb/d, PPAR-beta, PPARdelta, PPAR-delta, FAAR, NUCI, NR1C2, NUCII, PPARB, MGC3931, PPARBETA, ppard, pparb, PPARD

Auf Proteinebene tauchen folgende Bezeichner für Antigen Peroxisome Proliferator-Activated Receptor delta auf:

peroxisome proliferator activator receptor delta – mPPAR(delta) – PPARdelta/beta – OTTMUSP00000027308 – Peroxisome proliferator-activated receptor beta – peroxisome proliferative activated receptor, delta – OTTHUMP00000016256 – OTTHUMP00000016257 – nuclear hormone receptor 1 – peroxisome proliferator-activated receptor delta – peroxisome proliferator-activated receptor beta – PPAR-beta – PPAR-delta – nuclear receptor subfamily 1 group C member 2 – peroxisome proliferator-activated receptor delta-like

Peroxisome Proliferator-Activated Receptor delta erfüllt eine Reihe von Funktionen:

DNA binding – enzyme activator activity – ligand-dependent nuclear receptor activity – metal ion binding – prostacyclin receptor activity – protein binding – protein heterodimerization activity – receptor activity – retinoid X receptor binding – sequence-specific DNA binding – steroid hormone receptor activity – transcription factor activity – transcription repressor activity – zinc ion binding – NF-kappaB binding – drug binding – linoleic acid binding – transcription activator activity – lipid binding – sequence-specific DNA binding transcription factor activity

Peroxisome Proliferator-Activated Receptor delta spielt in den folgenden Prozessen eine Rolle:

adipose tissue development – anagen – axon ensheathment – cell differentiation – cell proliferation – cell-substrate adhesion – cellular process – embryo implantation – epidermis development – fatty acid beta-oxidation – fatty acid transport – keratinocyte migration – keratinocyte proliferation – lipid metabolic process – negative regulation of epithelial cell proliferation – negative regulation of transcription from RNA polymerase II promoter – placenta development – positive regulation of cell proliferation – positive regulation of phosphoinositide 3-kinase cascade – regulation of cell proliferation – regulation of fat cell differentiation – regulation of insulin secretion – regulation of transcription – regulation of transcription, DNA-dependent – transcription – wound healing – apoptosis – cholesterol metabolic process – decidualization – generation of precursor metabolites and energy – glucose metabolic process – glucose transport – positive regulation of fat cell differentiation – vitamin A metabolic process

Peroxisome Proliferator-Activated Receptor delta ist wie folgt lokalisiert:

nucleus

Quelle: NCBI Entrez Gene, Gene Ontology