Die folgenden Gennamen und Gensymbole werden für Antigen Peroxisome Proliferative Activated Receptor gamma über verschiedene Spezies hinweg verwendet:

peroxisome proliferator-activated receptor gamma (PPARG), peroxisome proliferative activated receptor gamma (LOC100231741)

Zu den weiteren Synonymen zählen:

GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma, PPARG

Auf Proteinebene tauchen folgende Bezeichner für Antigen Peroxisome Proliferative Activated Receptor gamma auf:

peroxisome proliferative activated receptor gamma – PPAR gamma – OTTHUMP00000185030 – OTTHUMP00000185033 – nuclear receptor subfamily 1 group C member 3 – peroxisome proliferator-activated receptor gamma 1 – peroxisome proliferator-activated receptor gamma

Peroxisome Proliferative Activated Receptor gamma erfüllt eine Reihe von Funktionen:

arachidonic acid binding – drug binding – metal ion binding – prostaglandin receptor activity – protein heterodimerization activity – retinoid X receptor binding – sequence-specific DNA binding – steroid hormone receptor activity – transcription activator activity – transcription activator binding – transcription factor activity – transcription repressor activity – zinc ion binding

Peroxisome Proliferative Activated Receptor gamma spielt in den folgenden Prozessen eine Rolle:

brown fat cell differentiation – cell fate commitment – cell maturation – cellular response to insulin stimulus – epithelial cell differentiation – glucose homeostasis – innate immune response – lipid homeostasis – lipid metabolic process – lipoprotein transport – long-chain fatty acid transport – low-density lipoprotein receptor biosynthetic process – monocyte differentiation – negative regulation of cell proliferation – negative regulation of cholesterol storage – negative regulation of cytokine production – negative regulation of gene-specific transcription from RNA polymerase II promoter – negative regulation of macrophage derived foam cell differentiation – negative regulation of receptor biosynthetic process – negative regulation of sequestering of triglyceride – placenta development – positive regulation of fat cell differentiation – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of transcription – regulation of blood pressure – response to lipid – response to low density lipoprotein stimulus – response to nutrient – signal transduction – white fat cell differentiation

Peroxisome Proliferative Activated Receptor gamma ist wie folgt lokalisiert:

cytosol – nucleus

Quelle: NCBI Entrez Gene, Gene Ontology