Die folgenden Gennamen und Gensymbole werden für Antigen Paxillin über verschiedene Spezies hinweg verwendet:

paxillin (PXN), paxillin (Pxn), Paxillin (Pax), paxillin (LOC397826), paxillin (pxn), paxillin (LOC100220858)

Zu den weiteren Synonymen zählen:

FLJ16691, Pax, AW108311, AW123232, CG18061, CG18576, CT40481, CT42454, DPaxillin, DPxn, DPxn37, Dpax, PDLP, DmelCG31794, CG31794, LOC397826, wu:fw71f12, PXN, DKFZp469J2119, LOC100220858

Auf Proteinebene tauchen folgende Bezeichner für Antigen Paxillin auf:

paxillin – OTTMUSP00000015574 – OTTMUSP00000015575 – paxillin, isoform C – CG31794-PC – Pax-PC – paxillin-derived LIM-only protein – paxillin, isoform G – CG31794-PG – Pax-PG – paxillin, isoform F – CG31794-PF – Pax-PF – paxillin, isoform B – CG31794-PB – Pax-PB – paxillin, isoform A – CG31794-PA – Pax-PA – paxillin, isoform D – CG31794-PD – Pax-PD – myocardial ischemic preconditioning associated protein 7

Paxillin erfüllt eine Reihe von Funktionen:

metal ion binding – protein binding – vinculin binding – zinc ion binding – BH4 domain binding – integrin binding – protein complex binding – protein kinase binding – receptor signaling complex scaffold activity – beta-catenin binding

Paxillin spielt in den folgenden Prozessen eine Rolle:

cell adhesion – cell-matrix adhesion – cellular response to reactive oxygen species – signal complex assembly – signal transduction – activation of MAPK activity – branching morphogenesis of a tube – cellular component movement – cytoskeleton organization – focal adhesion assembly – integrin-mediated signaling pathway – lamellipodium assembly – peptidyl-tyrosine phosphorylation – cytoskeletal anchoring at plasma membrane – muscle contraction – embryonic development – somitogenesis

Paxillin ist wie folgt lokalisiert:

cell junction – cytoplasm – cytoskeleton – focal adhesion – lamellipodium – microtubule associated complex – plasma membrane – cell leading edge

Quelle: NCBI Entrez Gene, Gene Ontology