Die folgenden Gennamen und Gensymbole werden für Antigen Patched über verschiedene Spezies hinweg verwendet:

patched (ptc), patched (patch), patched homolog 1 (ptch1), patched (PTCH1), patched receptor (patched)

Zu den weiteren Synonymen zählen:

BcDNA:RH36596, Conf, PTC, Ptc_Dm, Ptch, dPtc, l(2)k02507, pat, rubr, tuf, DmelCG2411, CG2411, ptc1, XPtc1, patched, patched1, PTCH1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Patched auf:

patched – CG2411-PA – ptc-PA – confused – tufted – rubberneck – patch – patched homolog 1 – patched-1 – patched receptor

Patched erfüllt eine Reihe von Funktionen:

hedgehog receptor activity – lipoprotein receptor activity – protein binding – transmembrane receptor activity

Patched spielt in den folgenden Prozessen eine Rolle:

Bolwig's organ morphogenesis – anterior/posterior lineage restriction, imaginal disc – anterior/posterior pattern formation – axon guidance – blastoderm segmentation – dephosphorylation – determination of genital disc primordium – embryonic pattern specification – eye-antennal disc morphogenesis – germ-line stem cell division – imaginal disc-derived wing morphogenesis – lipid homeostasis – negative regulation of smoothened signaling pathway – oogenesis – ovarian follicle cell development – peripheral nervous system development – proteolysis – regulation of mitotic cell cycle – regulation of protein import into nucleus – smoothened signaling pathway – somatic stem cell division – wing disc anterior/posterior pattern formation

Patched ist wie folgt lokalisiert:

cytoplasm – endocytic vesicle – fusome – integral to membrane – integral to plasma membrane – perinuclear region of cytoplasm – plasma membrane

Quelle: NCBI Entrez Gene, Gene Ontology