Die folgenden Gennamen und Gensymbole werden für Antigen Par-3 Partitioning Defective 3 Homolog (C. Elegans) über verschiedene Spezies hinweg verwendet:

par-3 partitioning defective 3 homolog (C. elegans) (PARD3), par-3 (partitioning defective 3) homolog (C. elegans) (Pard3), par-3 partitioning defective 3 homolog (C. elegans) (pard3)

Zu den weiteren Synonymen zählen:

Baz, ASIP, PAR3, PARD3A, Bazooka, SE2-5T2, FLJ21015, SE2-5L16, SE2-5LT1, PAR3alpha, Par3

Auf Proteinebene tauchen folgende Bezeichner für Antigen Par-3 Partitioning Defective 3 Homolog (C. Elegans) auf:

partitioning-defective protein 3 homolog – atypical PKC isotype-specific interacting protein – partitioning defective 3 homolog – ASBP – ASIP – PARD-3 – partitioning-defective 3 homolog – atypical PKC-specific binding protein – atypical PKC-specific-binding protein – atypical PKC isotype-specific-interacting protein – three-PDZ containing protein similar to C. elegans PAR3 (partitioning defect) – par-3 partitioning defective 3 homolog (C. elegans)

Par-3 Partitioning Defective 3 Homolog (C. Elegans) erfüllt eine Reihe von Funktionen:

protein binding – lipid binding – phosphatidylinositol-3,4,5-trisphosphate binding – phosphatidylinositol-3-phosphate binding – phosphatidylinositol-4,5-bisphosphate binding – protein kinase C binding – protein phosphatase binding

Par-3 Partitioning Defective 3 Homolog (C. Elegans) spielt in den folgenden Prozessen eine Rolle:

activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway – asymmetric cell division – axonogenesis – cell cycle – establishment or maintenance of cell polarity – protein complex assembly – cell division – establishment of epithelial cell polarity – establishment or maintenance of epithelial cell apical/basal polarity – protein targeting to membrane – tight junction assembly

Par-3 Partitioning Defective 3 Homolog (C. Elegans) ist wie folgt lokalisiert:

cell cortex – cell junction – cytoplasm – endomembrane system – plasma membrane – tight junction – adherens junction – cell-cell adherens junction – cell-cell junction – cytoskeleton – membrane – protein complex – spindle

Quelle: NCBI Entrez Gene, Gene Ontology