Die folgenden Gennamen und Gensymbole werden für Antigen PTEN Induced Putative Kinase 1 über verschiedene Spezies hinweg verwendet:

PTEN induced putative kinase 1 (PINK1), PTEN-induced putative kinase 1 (Pink1), PTEN induced putative kinase 1 (Pink1), PTEN induced putative kinase 1 (pink1)

Zu den weiteren Synonymen zählen:

BRPK, PARK6, FLJ27236, BEST:GH23468, PINK1, dPINK1, DmelCG4523, CG4523, AU042772, AW557854, mFLJ00387, 1190006F07Rik, MGC189438, wu:fc39e12, zgc:101729

Auf Proteinebene tauchen folgende Bezeichner für Antigen PTEN Induced Putative Kinase 1 auf:

PTEN induced putative kinase 1 – protein kinase BRPK – serine/threonine-protein kinase PINK1 – PTEN-induced putative kinase 1, isoform H – CG4523-PH – Pink1-PH – PTEN-Induced kinase 1 – PTEN-induced putative kinase 1, isoform G – CG4523-PG – Pink1-PG – PTEN-induced putative kinase 1, isoform F – CG4523-PF – Pink1-PF – PTEN-induced putative kinase 1, isoform E – CG4523-PE – Pink1-PE – PTEN-induced putative kinase 1, isoform C – CG4523-PC – Pink1-PC – PTEN-induced putative kinase 1, isoform A – CG4523-PA – Pink1-PA – PTEN-induced putative kinase 1, isoform B – CG4523-PB – Pink1-PB – PTEN-induced putative kinase 1, isoform D – CG4523-PD – Pink1-PD – serine/threonine-protein kinase PINK1, mitochondrial – OTTMUSP00000010580 – PTEN-induced putative kinase protein 1 – serine/threonine-protein kinase PINK1, mitochondrial-like

PTEN Induced Putative Kinase 1 erfüllt eine Reihe von Funktionen:

ATP binding – magnesium ion binding – nucleotide binding – protein serine/threonine kinase activity – transferase activity – protein kinase activity – kinase activity – metal ion binding – C3HC4-type RING finger domain binding – calcium-dependent protein kinase activity – molecular_function

PTEN Induced Putative Kinase 1 spielt in den folgenden Prozessen eine Rolle:

positive regulation of dopamine secretion – positive regulation of synaptic transmission, dopaminergic – protein amino acid phosphorylation – protein kinase cascade – response to stress – compound eye development – mitochondrial fission – mitochondrion organization – negative regulation of programmed cell death – response to oxidative stress – sperm mitochondrion organization – phosphorylation – positive regulation of catecholamine secretion – biological_process – intracellular protein kinase cascade – peptidyl-serine phosphorylation – positive regulation of I-kappaB kinase/NF-kappaB cascade – positive regulation of release of cytochrome c from mitochondria – regulation of protein complex assembly – regulation of protein ubiquitination – neuron apoptosis – semicircular canal development

PTEN Induced Putative Kinase 1 ist wie folgt lokalisiert:

integral to membrane – membrane – mitochondrial outer membrane – mitochondrion – Nebenkern – mitochondrial inner membrane – cytosol

Quelle: NCBI Entrez Gene, Gene Ontology