Die folgenden Gennamen und Gensymbole werden für Antigen PI3-Kinase über verschiedene Spezies hinweg verwendet:

Phosphotidylinositol 3 kinase 68D (Pi3K68D), Pi3K92E, isoform A (Pi3K92E)

Zu den weiteren Synonymen zählen:

BcDNA:LD15217, Cpk, PI(3)K, PI3K, PI3K 68D, PI3K 68_D, PI3K-68D, PI3K-68D/E, PI3K68D, PI3K_68D, PI[[3]]K, dPI3K, dPIK, DmelCG11621, CG11621, Dmp110, Dp110, Dp110/PI3K, PI-3 kinase, PI-3-K, PI3K-92D, PI3K-92E/Dp110, PI3K-Dp110, PI3K92E, Pi3K92D, Pi3Kp110, anon-92Ed, p110, p120, rea, type-1 PI3K, DmelCG4141, CG4141

Auf Proteinebene tauchen folgende Bezeichner für Antigen PI3-Kinase auf:

phosphotidylinositol 3 kinase 68D, isoform C – CG11621-PC – Pi3K68D-PC – dPI 3-kinase – PI3-kinase – PI 3-kinase – phosphotidylinositol 3 kinase 68D, isoform A – CG11621-PA – Pi3K68D-PA – phosphotidylinositol 3 kinase 68D, isoform B – CG11621-PB – Pi3K68D-PB – Pi3K92E, isoform A – CG4141-PA – Pi3K92E-PA – phosphoinositide 3-kinase – p110 PI3 kinase – phosphatidylinositol 3-kinase – insulin-regulated PI3 kinase – PI3 kinase – Pi3K92E, isoform B – CG4141-PB – Pi3K92E-PB

PI3-Kinase erfüllt eine Reihe von Funktionen:

1-phosphatidylinositol-3-kinase activity – phosphatidylinositol-4,5-bisphosphate 3-kinase activity – phosphatidylinositol-4-phosphate 3-kinase activity – phosphoinositide 3-kinase activity – phosphoinositide binding – phospholipid binding – protein binding – binding – lipid kinase activity

PI3-Kinase spielt in den folgenden Prozessen eine Rolle:

cellular response to DNA damage stimulus – phagocytosis, engulfment – phosphoinositide phosphorylation – phosphoinositide-mediated signaling – autophagy – cell growth – germ-band shortening – instar larval development – insulin receptor signaling pathway – larval development – larval feeding behavior – larval salivary gland morphogenesis – metamorphosis – oogenesis – phosphorylation – positive regulation of cell growth – positive regulation of cell size – positive regulation of growth – positive regulation of imaginal disc growth – positive regulation of organ growth – regulation of cell proliferation – regulation of cell size – regulation of multicellular organism growth – regulation of organ growth – response to oxidative stress

PI3-Kinase ist wie folgt lokalisiert:

phosphoinositide 3-kinase complex – 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex

Quelle: NCBI Entrez Gene, Gene Ontology