Die folgenden Gennamen und Gensymbole werden für Antigen P38 MAP Kinase über verschiedene Spezies hinweg verwendet:

mitogen-activated protein kinase 14 (MAPK14), Mpk2, isoform B (Mpk2), mitogen activated protein kinase 14 (Mapk14)

Zu den weiteren Synonymen zählen:

RK, p38, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA, D-MPK2, D-P38a, D-p38, DMPK2, DmMPK2, Dp38, Erk2, P38, group 2, p38 alpha, p38A, DmelCG5475, CG5475, Hog, CRK1, CSBP, Exip, Csbp1, Csbp2, Prkm14, Prkm15, Sapk2A, p38Hog, p38alpha, MGC105413

Auf Proteinebene tauchen folgende Bezeichner für Antigen P38 MAP Kinase auf:

mitogen-activated protein kinase 14 – p38alpha Exip – p38 MAP kinase – MAP kinase Mxi2 – Csaids binding protein – MAX-interacting protein 2 – stress-activated protein kinase 2A – p38 mitogen activated protein kinase – cytokine suppressive anti-inflammatory drug binding protein – Mpk2, isoform B – CG5475-PB – Mpk2-PB – p38a MAP kinase – stress-activated kinase P38 – Erk-kinase-like – Mpk2, isoform A – CG5475-PA – Mpk2-PA – MAPK 14 – MAP kinase 2 – MAP kinase 14 – reactive kinase – MAP kinase p38 alpha – mitogen-activated protein kinase 14A – mitogen-activated protein kinase p38 alpha – cytokine-supressive anti-inflammatory drug binding protein

P38 MAP Kinase erfüllt eine Reihe von Funktionen:

ATP binding – MAP kinase activity – MAP kinase kinase activity – MP kinase activity – nucleotide binding – protein binding – protein serine/threonine kinase activity – transferase activity – SAP kinase activity – protein C-terminus binding

P38 MAP Kinase spielt in den folgenden Prozessen eine Rolle:

DNA damage checkpoint – Ras protein signal transduction – angiogenesis – cell motion – chemotaxis – chondrocyte differentiation – fatty acid oxidation – glucose metabolic process – lipopolysaccharide-mediated signaling pathway – positive regulation of erythrocyte differentiation – positive regulation of transcription from RNA polymerase II promoter – protein amino acid phosphorylation – protein kinase cascade – response to lipopolysaccharide – response to muramyl dipeptide – response to stress – skeletal muscle tissue development – MAPKKK cascade – defense response – immune response – negative regulation of antimicrobial humoral response – response to osmotic stress – signal transduction – cell morphogenesis – intracellular protein kinase cascade – protein amino acid autophosphorylation – response to glucose stimulus – stress-activated MAPK cascade

P38 MAP Kinase ist wie folgt lokalisiert:

cell – cytoplasm – cytosol – nucleoplasm – nucleus – spindle pole – cytosolic part – soluble fraction

Quelle: NCBI Entrez Gene, Gene Ontology