Die folgenden Gennamen und Gensymbole werden für Antigen P (Granule Membrane Protein 140kDa, Antigen CD62) über verschiedene Spezies hinweg verwendet:

selectin P (granule membrane protein 140kDa, antigen CD62) (SELP), selectin, platelet (Selp), selectin P (Selp), selectin P (SELP)

Zu den weiteren Synonymen zählen:

CD62, GRMP, PSEL, CD62P, GMP140, LECAM3, PADGEM, FLJ45155, Grmp, MGC129336, MGC129337, P-selectin, PSELECT, MGC124632, SELP

Auf Proteinebene tauchen folgende Bezeichner für Antigen P (Granule Membrane Protein 140kDa, Antigen CD62) auf:

selectin P – OTTHUMP00000032609 – granulocyte membrane protein – platelet alpha-granule membrane protein – leukocyte-endothelial cell adhesion molecule 3 – P-selectin – LECAM3 – GMP-140 – P selectin – granule membrane protein 140 – CD62 antigen-like family member P – platelet activation dependent granule-external membrane protein – PADGEM – selectin, platelet – selectin P (granule membrane protein 140kDa, antigen CD62) – p-selectin

P (Granule Membrane Protein 140kDa, Antigen CD62) erfüllt eine Reihe von Funktionen:

fucose binding – glycosphingolipid binding – heparin binding – lipopolysaccharide binding – oligosaccharide binding – protein binding – sialic acid binding – sugar binding – binding – calcium-dependent protein binding – eukaryotic cell surface binding – glycoprotein binding

P (Granule Membrane Protein 140kDa, Antigen CD62) spielt in den folgenden Prozessen eine Rolle:

cell adhesion – defense response to Gram-negative bacterium – leukocyte adhesion – positive regulation of platelet activation – response to lipopolysaccharide – blood vessel morphogenesis – cell-cell adhesion – cellular response to interleukin-6 – heterophilic cell-cell adhesion – inflammatory response – leukocyte cell-cell adhesion – leukocyte migration – leukocyte tethering or rolling – positive regulation of cell adhesion – positive regulation of leukocyte migration – regulation of cellular extravasation – response to organic cyclic substance

P (Granule Membrane Protein 140kDa, Antigen CD62) ist wie folgt lokalisiert:

external side of plasma membrane – extracellular space – integral to plasma membrane – membrane fraction – plasma membrane – platelet alpha granule membrane – soluble fraction – integral to membrane – membrane – platelet dense granule membrane

Quelle: NCBI Entrez Gene, Gene Ontology