Die folgenden Gennamen und Gensymbole werden für Antigen Nucleotide-Binding Oligomerization Domain Containing 1 über verschiedene Spezies hinweg verwendet:

nucleotide-binding oligomerization domain containing 1 (NOD1)

Zu den weiteren Synonymen zählen:

CARD4, NLRC1, CLR7.1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Nucleotide-Binding Oligomerization Domain Containing 1 auf:

nucleotide-binding oligomerization domain containing 1 – NLR family, CARD domain containing 1 – caspase recruitment domain family, member 4 – caspase recruitment domain-containing protein 4 – nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1

Nucleotide-Binding Oligomerization Domain Containing 1 erfüllt eine Reihe von Funktionen:

ATP binding – CARD domain binding – caspase activator activity – identical protein binding – nucleotide binding – peptidoglycan binding

Nucleotide-Binding Oligomerization Domain Containing 1 spielt in den folgenden Prozessen eine Rolle:

activation of caspase activity – defense response to Gram-positive bacterium – detection of bacterium – induction of apoptosis – inflammatory response – interleukin-8 biosynthetic process – intracellular signaling cascade – positive regulation of ERK1 and ERK2 cascade – positive regulation of I-kappaB kinase/NF-kappaB cascade – positive regulation of JNK cascade – positive regulation of interleukin-6 production – positive regulation of stress-activated MAPK cascade – positive regulation of tumor necrosis factor production – protein oligomerization – regulation of apoptosis

Nucleotide-Binding Oligomerization Domain Containing 1 ist wie folgt lokalisiert:

cytoplasm – intracellular

Quelle: NCBI Entrez Gene, Gene Ontology