Die folgenden Gennamen und Gensymbole werden für Antigen Nuclear Receptor Subfamily 1, Group I, Member 2 über verschiedene Spezies hinweg verwendet:

nuclear receptor subfamily 1, group I, member 2 (NR1I2), nuclear receptor subfamily 1, group I, member 2 (Nr1i2)

Zu den weiteren Synonymen zählen:

BXR, PAR, PRR, PXR, SAR, SXR, ONR1, PAR1, PAR2, PARq, PXR1, mPXR, PXR.1, PXR.2, MGC108643

Auf Proteinebene tauchen folgende Bezeichner für Antigen Nuclear Receptor Subfamily 1, Group I, Member 2 auf:

nuclear receptor subfamily 1, group I, member 2 – orphan nuclear receptor PXR – steroid and xenobiotic receptor – nuclear receptor subfamily 1 group I member 2 – OTTMUSP00000027962 – Pregnane X receptor – nuclear receptor subfamily 1, group 1, member 2 – pregnane X receptor (nuclear receptor sub family 1, group I, member 2)

Nuclear Receptor Subfamily 1, Group I, Member 2 erfüllt eine Reihe von Funktionen:

metal ion binding – protein binding – sequence-specific DNA binding – steroid hormone receptor activity – transcription coactivator activity – transcription factor activity – transcription repressor activity – zinc ion binding – DNA binding – ligand-dependent nuclear receptor activity – receptor activity – sequence-specific DNA binding transcription factor activity – drug binding

Nuclear Receptor Subfamily 1, Group I, Member 2 spielt in den folgenden Prozessen eine Rolle:

negative regulation of transcription – regulation of transcription, DNA-dependent – signal transduction – steroid metabolic process – xenobiotic metabolic process – regulation of transcription – transcription – drug export – exogenous drug catabolic process – positive regulation of transcription – xenobiotic transport

Nuclear Receptor Subfamily 1, Group I, Member 2 ist wie folgt lokalisiert:

nucleus

Quelle: NCBI Entrez Gene, Gene Ontology