Die folgenden Gennamen und Gensymbole werden für Antigen Nuclear Receptor Corepressor 2 über verschiedene Spezies hinweg verwendet:

nuclear receptor co-repressor 2 (NCOR2), nuclear receptor co-repressor 2 (Ncor2), similar to nuclear receptor co-repressor 2 (NCOR2), nuclear receptor co-repressor 2 (ncor2), nuclear receptor corepressor 2 (NCOR2)

Zu den weiteren Synonymen zählen:

SMRT, CTG26, SMRTE, TRAC1, TNRC14, TRAC-1, SMRTE-tau, N-CoR, SMRTe, NCOR2, gb:be017685, si:bz71m17.2, smrt, ctg26, smrte, trac1, tnrc14, trac-1, smrte-tau

Auf Proteinebene tauchen folgende Bezeichner für Antigen Nuclear Receptor Corepressor 2 auf:

nuclear receptor co-repressor 2 – silencing mediator for retinoid and thyroid hormone receptors – silencing mediator of retinoid acid and thyroid hormone receptor – silencing mediator – thyroid hormone receptor – nuclear receptor corepressor 2

Nuclear Receptor Corepressor 2 erfüllt eine Reihe von Funktionen:

DNA binding – Notch binding – protein N-terminus binding – transcription corepressor activity – transcription repressor binding – chromatin binding – protein binding – sequence-specific DNA binding – specific transcriptional repressor activity – transcription repressor activity – receptor activity

Nuclear Receptor Corepressor 2 spielt in den folgenden Prozessen eine Rolle:

negative regulation of gene-specific transcription from RNA polymerase II promoter – regulation of transcription – cell proliferation in forebrain – forebrain development – glucose homeostasis – heart morphogenesis – in utero embryonic development – negative regulation of fat cell differentiation – negative regulation of transcription – negative regulation of transcription from RNA polymerase II promoter – negative regulation of transcription, DNA-dependent – telencephalon development – transcription – white fat cell differentiation – regulation of transcription, DNA-dependent

Nuclear Receptor Corepressor 2 ist wie folgt lokalisiert:

nuclear body – nucleolus – nucleus – transcriptional repressor complex – histone deacetylase complex

Quelle: NCBI Entrez Gene, Gene Ontology