Die folgenden Gennamen und Gensymbole werden für Antigen Nuclear Receptor Coactivator 2 über verschiedene Spezies hinweg verwendet:

nuclear receptor coactivator 2 (NCOA2), nuclear receptor coactivator 2 (Ncoa2), nuclear receptor coactivator 2 (ncoa2)

Zu den weiteren Synonymen zählen:

SRC2, TIF2, GRIP1, KAT13C, NCoA-2, bHLHe75, MGC138808, Grip1, SRC-2, TIF-2, GRIP-1, 9530095N19, D1Ertd433e, tif2, wu:fc41a10, wu:fe26a11, Tif2, NCOA2, XTIF2, grip1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Nuclear Receptor Coactivator 2 auf:

nuclear receptor coactivator 2 – glucocorticoid receptor-interacting protein-1 – NCoA-2 – TIF2/GRIP-1 – OTTMUSP00000024144 – OTTMUSP00000024153 – transcriptional intermediary factor 2 – glucocorticoid receptor interacting protein 1 – glucocorticoid receptor-interacting protein 1 – src2 – grip1 – steroid receptor coactivator 2 – transcriptional intermediary factor-2 – Transcriptional intermediary factor 2 – nuclear receptor coactivator 2-like

Nuclear Receptor Coactivator 2 erfüllt eine Reihe von Funktionen:

nuclear hormone receptor binding – receptor binding – signal transducer activity – thyroid hormone receptor coactivator activity – transcription repressor activity – DNA binding – PDZ domain binding – chromatin binding – ligand-dependent nuclear receptor transcription coactivator activity – protein binding – receptor activity – transcription coactivator activity – transcription regulator activity – thyroid hormone receptor binding – ligand-dependent nuclear receptor binding

Nuclear Receptor Coactivator 2 spielt in den folgenden Prozessen eine Rolle:

negative regulation of transcription from RNA polymerase II promoter – positive regulation of transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – signal transduction – steroid hormone receptor signaling pathway – positive regulation of transcription – regulation of receptor activity – regulation of transcription – transcription – embryonic development – granulocyte differentiation – multicellular organismal development – myeloid cell differentiation – primitive hemopoiesis – cerebellum development

Nuclear Receptor Coactivator 2 ist wie folgt lokalisiert:

cytoplasm – nucleus – Golgi apparatus – dendrite – microtubule – neuronal cell body – postsynaptic density – presynaptic active zone – rough endoplasmic reticulum

Quelle: NCBI Entrez Gene, Gene Ontology