Die folgenden Gennamen und Gensymbole werden für Antigen Nuclear Receptor Coactivator 1 über verschiedene Spezies hinweg verwendet:

nuclear receptor coactivator 1 (NCOA1), nuclear receptor coactivator 1 (ncoa1), steroid receptor RNA activator 1 (SRA1), steroid receptor RNA activator 1 (Sra1), steroid receptor RNA activator 1 (sra1), steroid receptor RNA activator 1 (LOC100345921)

Zu den weiteren Synonymen zählen:

SRC1, KAT13A, RIP160, F-SRC-1, bHLHe42, bHLHe74, MGC129719, MGC129720, NCOA1, si:dkey-5g7.6, si:dkey-34f16.6, SRA, SRAP, STRAA1, pp7684, MGC87674, Sra, Srap, Straa1, Strra1, AA959952, zgc:86613, SRA1, MGC128615, DKFZp459C083

Auf Proteinebene tauchen folgende Bezeichner für Antigen Nuclear Receptor Coactivator 1 auf:

nuclear receptor coactivator 1 – Hin-2 protein – OTTHUMP00000155181 – OTTHUMP00000155182 – PAX3/NCOA1 fusion protein – steroid receptor coactivator-1 – SRC1 – DKEY-34F16.7 – steroid receptor RNA activator 1 – steroid receptor coactivator – steriod receptor RNA activator 1 – steriod receptor RNA activator protein – steroid receptor RNA activator 1 (complexes with NCOA1) – steroid receptor RNA activator protein

Nuclear Receptor Coactivator 1 erfüllt eine Reihe von Funktionen:

DNA binding – acyltransferase activity – androgen receptor binding – chromatin binding – histone acetyltransferase activity – nuclear hormone receptor binding – protein N-terminus binding – signal transducer activity – transcription coactivator activity – transcription regulator activity – transferase activity – protein binding – receptor activity – ligand-dependent nuclear receptor transcription coactivator activity – transcription cofactor activity – molecular_function

Nuclear Receptor Coactivator 1 spielt in den folgenden Prozessen eine Rolle:

androgen receptor signaling pathway – positive regulation of transcription from RNA polymerase II promoter – signal transduction – regulation of transcription, DNA-dependent – regulation of transcription – transcription – apoptosis – cell differentiation – cell proliferation – regulation of transcription from RNA polymerase II promoter – biological_process

Nuclear Receptor Coactivator 1 ist wie folgt lokalisiert:

nucleus – cell leading edge – cytoplasm – ribonucleoprotein complex – transcription factor complex – steroid hormone aporeceptor complex – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology