Die folgenden Gennamen und Gensymbole werden für Antigen Nitric Oxide Synthase 3 (Endothelial Cell) über verschiedene Spezies hinweg verwendet:

nitric oxide synthase 2, inducible (NOS2), nitric oxide synthase 2, inducible (Nos2), nitric oxide synthase 3, endothelial cell (Nos3), nitric oxide synthase 3 (endothelial cell) (NOS3), inducible nitric oxide synthase (nos2), nitric oxide synthase 3 (endothelial cell) (nos3)

Zu den weiteren Synonymen zählen:

NOS, INOS, NOS2A, HEP-NOS, iNOS, Nos-2, Nos2a, i-NOS, NOS-II, eNOS, Nos-3, ecNOS, 2310065A03Rik, iNos, cNOS, EC-NOS, NOSIII, NOS3, NOS2, nos2, ECNOS

Auf Proteinebene tauchen folgende Bezeichner für Antigen Nitric Oxide Synthase 3 (Endothelial Cell) auf:

nitric oxide synthase 2A – NOS, type II – nitric oxide synthase, macrophage – nitric oxide synthase 2A (inducible, hepatocytes) – nitric oxide synthase, inducible – MAC-NOS – NOS type II – inducible NOS – macrophage NOS – OTTMUSP00000000202 – inducible NO synthase – inducible nitric oxide synthase – nitric oxide synthase 2, inducible, macrophage – nitric oxide synthase, endothelial – cNOS – EC-NOS – NOSIII – NOS type III – endothelial NOS – constitutive NOS – OTTMUSP00000028591 – OTTMUSP00000028592 – endothelial nitric oxide synthase – eNOS – nitric oxide synthase 3 – Nitric oxide synthase, inducible – nitric oxide synthase 2, inducible – nitric oxide synthase 3 (endothelial cell) – iNOS – nitric oxide synthase, endothelial-like

Nitric Oxide Synthase 3 (Endothelial Cell) erfüllt eine Reihe von Funktionen:

FAD binding – FMN binding – NADP or NADPH binding – arginine binding – cAMP-dependent protein kinase regulator activity – calcium ion binding – calmodulin binding – electron carrier activity – heme binding – nitric-oxide synthase activity – oxidoreductase activity – protein homodimerization activity – tetrahydrobiopterin binding – zinc ion binding – iron ion binding – metal ion binding – protein binding – amino acid binding – actin monomer binding – cadmium ion binding

Nitric Oxide Synthase 3 (Endothelial Cell) spielt in den folgenden Prozessen eine Rolle:

G-protein signaling, coupled to cGMP nucleotide second messenger – arginine catabolic process – blood vessel remodeling – defense response to Gram-negative bacterium – endothelial cell proliferation – innate immune response in mucosa – nitric oxide biosynthetic process – oxidation reduction – positive regulation of killing of cells of another organism – positive regulation of leukocyte mediated cytotoxicity – protein kinase cascade – regulation of blood pressure – regulation of cell proliferation – regulation of cellular respiration – regulation of heart contraction – regulation of insulin secretion – response to hypoxia – retinoic acid receptor signaling pathway – signal transduction – superoxide metabolic process – cGMP-mediated signaling – defense response to bacterium – inflammatory response – intracellular protein kinase cascade – ovulation from ovarian follicle – angiogenesis – lipopolysaccharide-mediated signaling pathway – lung development – negative regulation of calcium ion transport – negative regulation of cell proliferation – negative regulation of hydrolase activity – negative regulation of muscle hyperplasia – negative regulation of potassium ion transport – negative regulation of smooth muscle cell proliferation – positive regulation of angiogenesis – regulation of blood vessel size – regulation of sodium ion transport – smooth muscle hyperplasia – aging – response to lipopolysaccharide – anti-apoptosis – blood coagulation – endothelial cell migration – mitochondrion organization – positive regulation of guanylate cyclase activity – regulation of systemic arterial blood pressure by endothelin – response to fluid shear stress – negative regulation of platelet activation – positive regulation of vasodilation – response to heat

Nitric Oxide Synthase 3 (Endothelial Cell) ist wie folgt lokalisiert:

cortical cytoskeleton – cytoplasm – cytosol – intracellular – nucleus – perinuclear region of cytoplasm – peroxisome – Golgi apparatus – apical part of cell – cytoskeleton – membrane – nucleolus – plasma membrane – soluble fraction – caveola – Golgi membrane

Quelle: NCBI Entrez Gene, Gene Ontology