Die folgenden Gennamen und Gensymbole werden für Antigen Myeloid Differentiation Primary Response Gene (88) über verschiedene Spezies hinweg verwendet:

myeloid differentiation primary response gene (88) (MYD88), myeloid differentiation primary response gene (88) (myd88-b), myeloid differentiation primary response gene 88 (Myd88), Myd88 (Myd88), myeloid differentiation primary response gene (88) (myd88), myeloid differentiation primary response factor 88 (Myd88), MyD88 adaptor (myd88), myeloid differentiation factor 88 (myd88), myeloid differentiation response protein 88 (myd88), myeloid differentiation primary response gene 88 (myd88), interleukin-1 receptor-associated kinase 2 (IRAK2), interleukin-1 receptor-associated kinase 2 (Irak2), interleukin-1 receptor-associated kinase 2 (irak2), interleukin-1 receptor-associated kinase 2 (LOC100228175)

Zu den weiteren Synonymen zählen:

MYD88D, XMyD88, myd88d, MGC84928, DMMYD88, EP(2)2535, Kra, LD20892, MYD88, dMyD88, DmelCG2078, CG2078, zgc:103541, GB12344, NV10640, myd88, IRAK-2, MGC150550, AI649099, MGC102586, 6330415L08Rik, irak-2, MGC79591, IRAK2

Auf Proteinebene tauchen folgende Bezeichner für Antigen Myeloid Differentiation Primary Response Gene (88) auf:

myeloid differentiation primary response gene 88 – myeloid differentiation primary response protein MyD88-B – Toll/IL-1 receptor binding protein MyD88-B – myeloid differentiation primary response protein MyD88 – OTTMUSP00000018013 – Myd88 – CG2078-PA – Myd88-PA – krapfen – zMyD88 – myeloid differentiation primary response factor 88 – myeloid differentiation factor 88 – myeloid differentiation primary response gene (88) – myeloid differentiation primary response protein 88 – MyD88 adaptor – myeloid differentiation response protein 88 – interleukin-1 receptor-associated kinase 2 – interleukin-1 receptor associated kinase-2 – interleukin-1 receptor-associated kinase-like 2 – mu-IRAK-2 – OTTMUSP00000028052 – OTTMUSP00000028055 – interleukin-1 receptor-associated kinase 2c – IRAK-2

Myeloid Differentiation Primary Response Gene (88) erfüllt eine Reihe von Funktionen:

Toll binding – death receptor binding – protein binding – transmembrane receptor activity – receptor binding – ATP binding – NF-kappaB-inducing kinase activity – protein heterodimerization activity – protein homodimerization activity – protein kinase activity – identical protein binding – GTP binding

Myeloid Differentiation Primary Response Gene (88) spielt in den folgenden Prozessen eine Rolle:

MyD88-dependent toll-like receptor signaling pathway – Toll signaling pathway – anti-apoptosis – cytokine-mediated signaling pathway – immunoglobulin mediated immune response – inflammatory response – innate immune response – lipopolysaccharide-mediated signaling pathway – positive regulation of I-kappaB kinase/NF-kappaB cascade – positive regulation of JNK cascade – positive regulation of NF-kappaB transcription factor activity – positive regulation of chemokine biosynthetic process – positive regulation of smooth muscle cell proliferation – positive regulation of transcription from RNA polymerase II promoter – positive regulation of tumor necrosis factor production – regulation of cell proliferation – response to interleukin-1 – response to lipopolysaccharide – response to molecule of fungal origin – response to virus – type I interferon biosynthetic process – JNK cascade – cell surface receptor linked signaling pathway – defense response to Gram-positive bacterium – immune response – negative regulation of growth of symbiont in host – positive regulation of interleukin-17 production – positive regulation of interleukin-23 production – positive regulation of interleukin-6 production – positive regulation of lymphocyte proliferation – regulation of inflammatory response – response to peptidoglycan – signal transduction – transmembrane receptor protein serine/threonine kinase signaling pathway – antifungal humoral response – defense response – dorsal/ventral pattern formation – positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria – response to fungus – I-kappaB kinase/NF-kappaB cascade – response to molecule of bacterial origin – interleukin-1-mediated signaling pathway – negative regulation of NF-kappaB transcription factor activity – protein amino acid phosphorylation – regulation of cytokine-mediated signaling pathway – activation of NF-kappaB-inducing kinase activity – apoptosis – negative regulation of transcription factor activity – phosphorylation – protein amino acid autophosphorylation – regulation of apoptosis – SRP-dependent cotranslational protein targeting to membrane

Myeloid Differentiation Primary Response Gene (88) ist wie folgt lokalisiert:

cytoplasm – cytosol – intrinsic to membrane – cell surface – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology