Die folgenden Gennamen und Gensymbole werden für Antigen Mitogen-Activated Protein Kinase Kinase Kinase 5 über verschiedene Spezies hinweg verwendet:

mitogen-activated protein kinase kinase kinase 5 (MAP3K5), mitogen-activated protein kinase kinase kinase 5 (Map3k5), mitogen-activated protein kinase kinase kinase 5 (MAPKKK5)

Zu den weiteren Synonymen zählen:

ASK1, MEKK5, MAPKKK5, MAP3K5, Ask1, mitogen-activated protein kinase kinase kinase 5, MUD21.11, MUD21_11

Auf Proteinebene tauchen folgende Bezeichner für Antigen Mitogen-Activated Protein Kinase Kinase Kinase 5 auf:

mitogen-activated protein kinase kinase kinase 5 – MAP/ERK kinase kinase 5 – MAPK/ERK kinase kinase 5 – apoptosis signal regulating kinase 1

Mitogen-Activated Protein Kinase Kinase Kinase 5 erfüllt eine Reihe von Funktionen:

ATP binding – MAP kinase kinase kinase activity – caspase activator activity – magnesium ion binding – nucleotide binding – protein homodimerization activity – protein serine/threonine kinase activity – transferase activity – JUN kinase kinase kinase activity – mitogen-activated protein kinase kinase binding – protein heterodimerization activity – kinase activity

Mitogen-Activated Protein Kinase Kinase Kinase 5 spielt in den folgenden Prozessen eine Rolle:

MAPKKK cascade – activation of JUN kinase activity – apoptosis – induction of apoptosis by extracellular signals – interspecies interaction between organisms – protein amino acid phosphorylation – activation of JNKK activity – protein amino acid autophosphorylation – protein heterooligomerization – protein autophosphorylation

Mitogen-Activated Protein Kinase Kinase Kinase 5 ist wie folgt lokalisiert:

cell cortex – cytoplasm – nucleus – plasma membrane

Quelle: NCBI Entrez Gene, Gene Ontology