Die folgenden Gennamen und Gensymbole werden für Antigen Mitogen-Activated Protein Kinase 8/9 über verschiedene Spezies hinweg verwendet:

mitogen-activated protein kinase 8 (MAPK8), mitogen-activated protein kinase 8 (Mapk8)

Zu den weiteren Synonymen zählen:

JNK, JNK1, PRKM8, SAPK1, JNK1A2, JNK21B1/2, Prkm8, AI849689

Auf Proteinebene tauchen folgende Bezeichner für Antigen Mitogen-Activated Protein Kinase 8/9 auf:

mitogen-activated protein kinase 8 – OTTHUMP00000019552 – protein kinase JNK1 – JUN N-terminal kinase – JNK1 beta protein kinase – JNK1 alpha protein kinase – c-Jun N-terminal kinase 1 – stress-activated protein kinase JNK1 – mitogen-activated protein kinase 8 isoform JNK1 beta2 – mitogen-activated protein kinase 8 isoform JNK1 alpha1 – MAPK 8 – MAP kinase 8 – OTTMUSP00000019790 – OTTMUSP00000019791 – OTTMUSP00000019793 – OTTMUSP00000019794 – JNK1 beta1 protein kinase – mitogen activated protein kinase 8 – protein kinase mitogen-activated 8 – p54 gamma – SAPK gamma – c-jun NH2-terminal kinase

Mitogen-Activated Protein Kinase 8/9 erfüllt eine Reihe von Funktionen:

ATP binding – JUN kinase activity – MAP kinase activity – nucleotide binding – protein binding – protein serine/threonine kinase activity – transferase activity – kinase activity – protein kinase activity

Mitogen-Activated Protein Kinase 8/9 spielt in den folgenden Prozessen eine Rolle:

JUN phosphorylation – activation of pro-apoptotic gene products – cell motion – induction of apoptosis by extracellular signals – negative regulation of apoptosis – response to UV – response to stress – signal transduction – JNK cascade – induction of apoptosis in response to chemical stimulus – inflammatory response – neuron projection development – ossification – peptidyl-threonine phosphorylation – positive regulation of DNA replication – positive regulation of cell migration – positive regulation of microtubule polymerization – protein amino acid phosphorylation – regulation of transcription, DNA-dependent – response to cadmium ion – response to heat – response to hydrogen peroxide – response to osmotic stress – apoptosis – positive regulation of apoptosis – response to steroid hormone stimulus

Mitogen-Activated Protein Kinase 8/9 ist wie folgt lokalisiert:

cytosol – nucleoplasm – axon part – cytoplasm – dendrite cytoplasm – mitochondrion – nucleus – perikaryon – vesicle

Quelle: NCBI Entrez Gene, Gene Ontology