Die folgenden Gennamen und Gensymbole werden für Antigen Mitogen-Activated Protein Kinase 1 über verschiedene Spezies hinweg verwendet:

mitogen-activated protein kinase 1 (MAPK1), mitogen-activated protein kinase 6 (MAPK6), mitogen-activated protein kinase 1 (Mapk1), mitogen activated protein kinase 1 (Mapk1), mitogen-activated protein kinase 1 (mapk1), mitogen-activated protein kinase 1b (mapk1b), mitogen-activated protein kinase 1 (PfMAP1), ATMPK1 (MITOGEN-ACTIVATED PROTEIN KINASE 1); MAP kinase/ kinase (ATMPK1), mitogen-activated protein kinase 1 (PVX_084965), mitogen-activated protein kinase 1 (ATMPK1), mitogen-activated protein kinase 1 (Tsp_01601)

Zu den weiteren Synonymen zählen:

ERK, p38, p40, p41, ERK2, ERT1, MAPK2, PRKM1, PRKM2, P42MAPK, p41mapk, ERK3, PRKM6, p97MAPK, HsT17250, DKFZp686F03189, Erk2, Prkm1, C78273, p42mapk, AA407128, AU018647, 9030612K14Rik, zERK2, MAPK1, Xp42, erk, erk2, mapk, mpk1, xp42, mapk1a, MGC68934, ert1, mapk2, prkm1, prkm2, F14N23.9, F14N23_9, MITOGEN-ACTIVATED PROTEIN KINASE, MITOGEN-ACTIVATED PROTEIN KINASE 1, MPK1

Auf Proteinebene tauchen folgende Bezeichner für Antigen Mitogen-Activated Protein Kinase 1 auf:

mitogen-activated protein kinase 1 – protein tyrosine kinase ERK2 – mitogen-activated protein kinase 2 – extracellular signal-regulated kinase 2 – extracellular signal-regulated kinase-2 – mitogen-activated protein kinase 6 – MAP kinase isoform p97 – protein kinase, mitogen-activated 5 – protein kinase, mitogen-activated 6 – extracellular signal-regulated kinase 3 – extracellular signal-regulated kinase, p97 – ERT1 – ERK-2 – MAPK 1 – MAPK 2 – p42-MAPK – MAP kinase 1 – MAP kinase 2 – OTTMUSP00000021888 – OTTMUSP00000022009 – OTTMUSP00000022010 – MAP kinase isoform p42 – mitogen activated protein kinase 1 – extracellular-signal-regulated kinase 2 – ERK2 – myelin basic protein kinase-like protein – MAP kinase – mitogen-activated protein kinase 1a – ATMPK1 (MITOGEN-ACTIVATED PROTEIN KINASE 1); MAP kinase/ kinase

Mitogen-Activated Protein Kinase 1 erfüllt eine Reihe von Funktionen:

ATP binding – MAP kinase 2 activity – nucleotide binding – phosphotyrosine binding – protein binding – protein serine/threonine kinase activity – transferase activity – MAP kinase activity – RNA polymerase II carboxy-terminal domain kinase activity – kinase activity – mitogen-activated protein kinase kinase kinase binding – protein kinase activity – transcription factor binding – transcription regulator activity

Mitogen-Activated Protein Kinase 1 spielt in den folgenden Prozessen eine Rolle:

B cell receptor signaling pathway – MAPKKK cascade – Ras protein signal transduction – T cell receptor signaling pathway – cell cycle – chemotaxis – cytosine metabolic process – induction of apoptosis – interspecies interaction between organisms – lipopolysaccharide-mediated signaling pathway – negative regulation of cell differentiation – organ morphogenesis – protein amino acid phosphorylation – response to DNA damage stimulus – response to exogenous dsRNA – response to lipopolysaccharide – synaptic transmission – signal transduction – intracellular signaling pathway – labyrinthine layer blood vessel development – nuclear translocation of MAPK – peptidyl-serine phosphorylation – phosphorylation – positive regulation of translation – regulation of transcription factor activity – response to chemical stimulus – response to estrogen stimulus – response to toxin – sensory perception of pain – intracellular protein kinase cascade – positive regulation of cell migration – positive regulation of cell proliferation – positive regulation of transcription – small GTPase mediated signal transduction – gastrulation – auxin mediated signaling pathway

Mitogen-Activated Protein Kinase 1 ist wie folgt lokalisiert:

cytoplasm – cytoskeleton – cytosol – nucleolus – nucleoplasm – nucleus – axon part – dendrite cytoplasm – insoluble fraction – perikaryon – protein complex – soluble fraction – microtubule cytoskeleton – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology