Die folgenden Gennamen und Gensymbole werden für Antigen Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase über verschiedene Spezies hinweg verwendet:

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (MTHFD1), methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (Mthfd1), methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase (Mthfd1), methylenetetrahydrofolate dehydrogenase (NADP+ dependent) (mthfd1), c-1-tetrahydrofolate synthase, cytoplasmic (pug), C-1-tetrahydrofolate synthase, cytoplasmic (Tc00.1047053509509.20), C-1-tetrahydrofolate synthase, cytoplasmic (Tc00.1047053511741.50), C-1-tetrahydrofolate synthase, cytoplasmic (Tc00.1047053511517.60), C-1-tetrahydrofolate synthase, cytoplasmic (Tc00.1047053508207.240), C-1-tetrahydrofolate synthase, cytoplasmic (Tb927.7.1600), C-1-tetrahydrofolate synthase, cytoplasmic (LinJ26.0310), c-1-tetrahydrofolate synthase, cytoplasmic (LinJ30.2930), C-1-tetrahydrofolate synthase, cytoplasmic (LbrM26_V2.0350), c-1-tetrahydrofolate synthase, cytoplasmic (LbrM30_V2.2550), C-1-tetrahydrofolate synthase, cytoplasmic (LmjF26.0320), c-1-tetrahydrofolate synthase, cytoplasmic (LmjF30.2600), c-1-tetrahydrofolate synthase, cytoplasmic (Tsp_00651), C-1-tetrahydrofolate synthase, cytoplasmic (c1tc), methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (mthfd1), similar to C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) (MTHFD1)

Zu den weiteren Synonymen zählen:

MTHFC, MTHFD, Dcs, Mthfd, E430024A07Rik, cb325, zgc:55597, MGC137793, Tb07.27M11.970, MTHFD1, DKFZp469M2025, MGC53151, MGC79474

Auf Proteinebene tauchen folgende Bezeichner für Antigen Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase auf:

methylenetetrahydrofolate dehydrogenase 1 – C1-THF synthase – cytoplasmic C-1-tetrahydrofolate synthase – 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methylenetetrahydrofolate cyclohydrolase, 10-formyltetrahydrofolate synthetase – C1-tetrahydrofolate synthase – C-1-tetrahydrofolate synthase, cytoplasmic – methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase – formyltetrahydrofolate synthetase – methenyltetrahydrofolate cyclohydrolase – methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase – c-1-tetrahydrofolate synthase, cytoplasmic – pugilist – methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase – mthfd1 protein – c-1-tetrahydrofolate synthase, cytoplasmic-like

Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase erfüllt eine Reihe von Funktionen:

ATP binding – formate-tetrahydrofolate ligase activity – formyltetrahydrofolate dehydrogenase activity – hydrolase activity – ligase activity – methenyltetrahydrofolate cyclohydrolase activity – methylenetetrahydrofolate dehydrogenase (NADP+) activity – nucleotide binding – oxidoreductase activity – protein binding – binding – methylenetetrahydrofolate dehydrogenase activity – catalytic activity

Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase spielt in den folgenden Prozessen eine Rolle:

cellular amino acid biosynthetic process – folic acid and derivative biosynthetic process – histidine biosynthetic process – histidine catabolic process – methionine biosynthetic process – one-carbon metabolic process – oxidation reduction – purine nucleotide biosynthetic process – metabolic process – nucleotide metabolic process – tetrahydrofolate metabolic process

Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1, Methenyltetrahydrofolate Cyclohydrolase, Formyltetrahydrofolate Synthetase ist wie folgt lokalisiert:

cytoplasm – mitochondrion

Quelle: NCBI Entrez Gene, Gene Ontology