Die folgenden Gennamen und Gensymbole werden für Antigen Lymphocyte-Specific Protein tyrosine Kinase über verschiedene Spezies hinweg verwendet:

lymphocyte-specific protein tyrosine kinase (LCK), lymphocyte-specific protein tyrosine kinase (Lck), lymphocyte-specific protein tyrosine kinase (lck), lymphocyte-specific protein tyrosine kinase (LOC100349102)

Zu den weiteren Synonymen zählen:

YT16, p56lck, pp58lck, Lck1, Lcktkr, MGC136695, MGC194004, MGC194043, zgc:136695, LCK, MGC126900

Auf Proteinebene tauchen folgende Bezeichner für Antigen Lymphocyte-Specific Protein tyrosine Kinase auf:

lymphocyte-specific protein tyrosine kinase – protein tyrosine kinase – p56(LSTRA) protein-tyrosine kinase – proto-oncogene tyrosine-protein kinase LCK – T-lymphocyte specific protein tyrosine kinase p56lck – p56-LCK – lymphocyte protein tyrosine kinase – lymphocyte cell-specific protein-tyrosine kinase – tyrosine-protein kinase Lck-like

Lymphocyte-Specific Protein tyrosine Kinase erfüllt eine Reihe von Funktionen:

ATP binding – ATPase binding – CD4 receptor binding – CD8 receptor binding – SH2 domain binding – glycoprotein binding – non-membrane spanning protein tyrosine kinase activity – nucleotide binding – phosphoinositide 3-kinase binding – protein C-terminus binding – protein kinase binding – protein serine/threonine phosphatase activity – transferase activity – antigen binding – protein binding – protein complex binding – protein tyrosine kinase activity – kinase activity – protein kinase activity

Lymphocyte-Specific Protein tyrosine Kinase spielt in den folgenden Prozessen eine Rolle:

B cell receptor signaling pathway – T cell differentiation – activation of caspase activity – cell surface receptor linked signal transduction – cellular zinc ion homeostasis – hemopoiesis – induction of apoptosis – interspecies interaction between organisms – peptidyl-tyrosine phosphorylation – positive regulation of T cell activation – positive regulation of T cell receptor signaling pathway – positive regulation of gamma-delta T cell differentiation – protein amino acid autophosphorylation – regulation of lymphocyte activation – release of sequestered calcium ion into cytosol – response to drug – aging – apoptosis – cell surface receptor linked signaling pathway – positive regulation of uterine smooth muscle contraction – protein amino acid phosphorylation – regulation of T cell receptor signaling pathway – response to hydrogen peroxide – response to mechanical stimulus – response to metal ion – response to zinc ion

Lymphocyte-Specific Protein tyrosine Kinase ist wie folgt lokalisiert:

Golgi apparatus – cytoplasm – cytosol – internal side of plasma membrane – membrane raft – pericentriolar material – plasma membrane – endocytic vesicle – cellular_component

Quelle: NCBI Entrez Gene, Gene Ontology