Die folgenden Gennamen und Gensymbole werden für Antigen Leptin über verschiedene Spezies hinweg verwendet:

leptin (LEP), leptin (Lep)

Zu den weiteren Synonymen zählen:

OB, OBS, FLJ94114, ob, obese

Auf Proteinebene tauchen folgende Bezeichner für Antigen Leptin auf:

leptin – obesity factor – obese, mouse, homolog of – leptin (murine obesity homolog) – leptin (obesity homolog, mouse) – Obesity (murine homolog, leptin)

Leptin erfüllt eine Reihe von Funktionen:

growth factor activity – hormone activity – protein binding – cytokine activity – peptide hormone receptor binding

Leptin spielt in den folgenden Prozessen eine Rolle:

adult feeding behavior – bile acid metabolic process – central nervous system neuron development – cholesterol metabolic process – eating behavior – energy reserve metabolic process – glucose metabolic process – hormone metabolic process – lipid metabolic process – negative regulation of appetite – positive regulation of myeloid cell differentiation – regulation of gluconeogenesis – regulation of insulin secretion – regulation of intestinal cholesterol absorption – regulation of metabolic process – regulation of steroid biosynthetic process – response to dietary excess – response to insulin stimulus – signal transduction – insulin secretion – JAK-STAT cascade – cAMP-mediated signaling – fatty acid catabolic process – intracellular signaling cascade – leptin-mediated signaling pathway – negative regulation of metabolic process – ovulation from ovarian follicle – positive regulation of MAPKKK cascade

Leptin ist wie folgt lokalisiert:

extracellular region – extracellular space

Quelle: NCBI Entrez Gene, Gene Ontology