Die folgenden Gennamen und Gensymbole werden für Antigen Kruppel-Like Factor 4 (Gut) über verschiedene Spezies hinweg verwendet:

Kruppel-like factor 4 (gut) (KLF4), Kruppel-like factor 4 (gut) (Klf4), Kruppel-like transcription factor 4a (klf4a), Kruppel-like factor 4 (klf4)

Zu den weiteren Synonymen zählen:

EZF, GKLF, Zie, Gklf, MGC93286, KLF4, MGC139189

Auf Proteinebene tauchen folgende Bezeichner für Antigen Kruppel-Like Factor 4 (Gut) auf:

Kruppel-like factor 4 (gut) – endothelial Kruppel-like zinc finger protein – Krueppel-like factor 4 – gut-enriched krueppel-like factor – epithelial zinc finger protein EZF – Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF) – Kruppel-like factor 4

Kruppel-Like Factor 4 (Gut) erfüllt eine Reihe von Funktionen:

metal ion binding – transcription activator activity – transcription factor activity – transcription repressor activity – zinc ion binding – DNA binding – RNA polymerase II transcription factor activity – double-stranded DNA binding – nucleic acid binding – phosphoinositide 3-kinase regulator activity – promoter binding – sequence-specific DNA binding – sequence-specific DNA binding transcription factor activity

Kruppel-Like Factor 4 (Gut) spielt in den folgenden Prozessen eine Rolle:

mesodermal cell fate determination – negative regulation of cell proliferation – negative regulation of transcription, DNA-dependent – regulation of transcription – cell differentiation – epidermal cell differentiation – epidermis morphogenesis – negative regulation of ERK1 and ERK2 cascade – negative regulation of muscle hyperplasia – negative regulation of phosphoinositide 3-kinase cascade – negative regulation of protein kinase B signaling cascade – negative regulation of smooth muscle cell proliferation – negative regulation of transcription – positive regulation of transcription from RNA polymerase II promoter – post-embryonic camera-type eye development – regulation of cell proliferation – response to chemical stimulus – response to retinoic acid – stem cell maintenance – transcription

Kruppel-Like Factor 4 (Gut) ist wie folgt lokalisiert:

intracellular – nucleolus – nucleus – chromatin – transcription factor complex

Quelle: NCBI Entrez Gene, Gene Ontology