Die folgenden Gennamen und Gensymbole werden für Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) über verschiedene Spezies hinweg verwendet:

kinase insert domain protein receptor (Kdr), kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR), kinase insert domain receptor (Kdr), vascular endothelial growth factor receptor 2 (vegfr-2)

Zu den weiteren Synonymen zählen:

Flk1, Ly73, Flk-1, Krd-1, VEGFR2, VEGFR-2, sVEGFR-2, 6130401C07, FLK1, CD309, VEGFR, Vegfr-2, MGC93590, KDR, FLK-1, flk-1, vegfr-2

Auf Proteinebene tauchen folgende Bezeichner für Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) auf:

vascular endothelial growth factor receptor 2 – kinase NYK – VEGF receptor-2 – OTTMUSP00000023578 – fetal liver kinase 1 – protein-tyrosine kinase receptor flk-1 – vascular endothelial growth factor receptor-2 – vascular endothelial growth factor receptor-3 – vascular endothelial growth factor receptor- 2 – soluble vascular endothelial growth factor receptor 2 – kinase insert domain receptor – soluble VEGFR2 – fetal liver kinase-1 – protein-tyrosine kinase receptor Flk-1 – tyrosine kinase growth factor receptor – FLK-1 – kinase insert domain protein receptor – FLK1 kinase insert domain receptor (VEGF receptor 2) – FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2) – flk-1 receptor – kinase insert domain receptor (a type III receptor tyrosine kinase) – flk-1 type VEGF receptor – tyrosine kinase receptor

Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) erfüllt eine Reihe von Funktionen:

ATP binding – growth factor binding – kinase activity – nucleotide binding – protein binding – protein kinase activity – protein tyrosine kinase activity – receptor activity – transferase activity – transmembrane receptor protein tyrosine kinase activity – vascular endothelial growth factor receptor activity – integrin binding

Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) spielt in den folgenden Prozessen eine Rolle:

angiogenesis – branching morphogenesis of a tube – calcium ion homeostasis – cell differentiation – cell fate commitment – cell maturation – cell migration – elevation of cytosolic calcium ion concentration – endothelial cell differentiation – hemopoiesis – lung alveolus development – lung development – male gonad development – multicellular organismal development – neuron projection morphogenesis – neuroprotection – ovarian follicle development – phosphorylation – positive regulation of TOR signaling cascade – positive regulation of angiogenesis – positive regulation of calcium-mediated signaling – positive regulation of cell migration – positive regulation of cell proliferation – positive regulation of epithelial cell proliferation – positive regulation of long-term neuronal synaptic plasticity – positive regulation of mesenchymal cell proliferation – positive regulation of phosphoinositide 3-kinase cascade – positive regulation of vasodilation – protein amino acid autophosphorylation – protein amino acid phosphorylation – response to chemical stimulus – response to hypoxia – signal transduction – surfactant homeostasis – transmembrane receptor protein tyrosine kinase signaling pathway – vascular endothelial growth factor receptor signaling pathway – vasculogenesis – interspecies interaction between organisms – positive regulation of positive chemotaxis – regulation of cell shape – positive regulation of endothelial cell migration – positive regulation of endothelial cell proliferation – positive regulation of focal adhesion assembly – positive regulation of neurogenesis – response to drug

Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) ist wie folgt lokalisiert:

cytoplasm – integral to membrane – integral to plasma membrane – membrane – membrane fraction – neuron projection – neuronal cell body – plasma membrane

Quelle: NCBI Entrez Gene, Gene Ontology