Die folgenden Gennamen und Gensymbole werden für Antigen Kalirin, RhoGEF Kinase über verschiedene Spezies hinweg verwendet:

SEC14 and spectrin domains 1 (sestd1), kalirin, RhoGEF kinase (KALRN), kalirin, RhoGEF kinase (Kalrn), kalirin, RhoGEF kinase (kalrn), kalirin (Smp_162970)

Zu den weiteren Synonymen zählen:

duo, sol, HAPIP, cb248, sb:cb248, dZ106A20.1, si:dz42h5.2, si:dz106a20.1, si:dz106a20.2, DUO, DUET, TRAD, FLJ12332, FLJ16443, FLJ18196, FLJ18623, KALRN, Gm539, Hapip, AV235988, 2210407G14Rik, E530005C20Rik

Auf Proteinebene tauchen folgende Bezeichner für Antigen Kalirin, RhoGEF Kinase auf:

SEC14 domain and spectrin repeat-containing protein 1 – solo – protein Solo – huntingtin-associated – kalirin, RhoGEF kinase – huntingtin-associated protein interacting protein (duo) – serine/threonine kinase with Dbl- and pleckstrin homology domains – kalirin – protein Duo – OTTMUSP00000019357 – OTTMUSP00000019358 – OTTMUSP00000019359 – OTTMUSP00000019360 – OTTMUSP00000019361 – OTTMUSP00000019362 – OTTMUSP00000019363 – OTTMUSP00000019365 – serine/threonine kinase with Dbl- and pleckstrin homology domain – serine/threonine-protein kinase with Dbl- and pleckstrin homology domain – kalirin-like

Kalirin, RhoGEF Kinase erfüllt eine Reihe von Funktionen:

ATP binding – Rho guanyl-nucleotide exchange factor activity – guanyl-nucleotide exchange factor activity – magnesium ion binding – nucleotide binding – protein serine/threonine kinase activity – transferase activity – kinase activity – metal ion binding – protein kinase activity

Kalirin, RhoGEF Kinase spielt in den folgenden Prozessen eine Rolle:

blood vessel morphogenesis – intracellular signaling cascade – nervous system development – protein amino acid phosphorylation – regulation of Rho protein signal transduction – vesicle-mediated transport – axonogenesis – intracellular signaling pathway – regulation of dendrite development

Kalirin, RhoGEF Kinase ist wie folgt lokalisiert:

actin cytoskeleton – cytoplasm – intracellular – cytoskeleton – neuron projection – neuronal cell body – perinuclear region of cytoplasm

Quelle: NCBI Entrez Gene, Gene Ontology