Die folgenden Gennamen und Gensymbole werden für Antigen K(lysine) Acetyltransferase 5 über verschiedene Spezies hinweg verwendet:

K(lysine) acetyltransferase 5 (Kat5), zgc:92510 (zgc:92510), K(lysine) acetyltransferase 5 (LOC100340634), K(lysine) acetyltransferase 5 (KAT5), Tip60 (Tip60), histone acetyltransferase Tip60 (Tip60), tip60 (AaeL_AAEL014072), tip60 (Smp_053140)

Zu den weiteren Synonymen zählen:

PLIP, 60kDa, Tip55, Tip60, Htatip, Htatip1, AI839539, MGC117972, MGC95167, TIP, ESA1, TIP60, cPLA2, HTATIP, HTATIP1, 6121, CG6121, DmEG0007.7, Dmel/TIP60, DmelCG6121, DmelTIP60, dmHAG405, dTip60, dTIP60, EG0007.7, EG:EG0007.7

Auf Proteinebene tauchen folgende Bezeichner für Antigen K(lysine) Acetyltransferase 5 auf:

histone acetyltransferase KAT5 – mHTATIP/CPLA2 – Tat-interactive protein-60 – lysine acetyltransferase 5 – 60 kDa Tat-interactive protein – histone acetyltransferase HTATIP – HIV-1 tat interactive protein, homolog – HIV-1 tat interactive protein 1, homolog – HIV-1 tat interactive protein 1, 60 kDa homolog – HIV-1 Tat interactive protein 60 kD – HIV-1 Tat interactive protein, 60 kD – K(lysine) acetyltransferase 5 – K-acetyltransferase 5 – cPLA2 interacting protein – Tat interacting protein, 60kDa – HIV-1 Tat interactive protein, 60kDa – Tip60 – CG6121-PA – Tip60-PA – Tat-interactive protein – histone acetyltransferase Tip60 – tip60

K(lysine) Acetyltransferase 5 erfüllt eine Reihe von Funktionen:

acyltransferase activity – chromatin binding – histone acetyltransferase activity – metal ion binding – protein binding – protein complex binding – transcription coactivator activity – transcription factor binding – transferase activity – transferase activity, transferring acyl groups other than amino-acyl groups – transcription repressor activity – transcription repressor binding – androgen receptor binding – zinc ion binding

K(lysine) Acetyltransferase 5 spielt in den folgenden Prozessen eine Rolle:

chromatin assembly or disassembly – chromatin modification – histone acetylation – positive regulation of transcription – positive regulation of transcription from RNA polymerase II promoter – regulation of growth – regulation of transcription – transcription – DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator – double-strand break repair – histone H4 acetylation – negative regulation of gene-specific transcription from RNA polymerase II promoter – negative regulation of interleukin-2 production – positive regulation of transcription, DNA-dependent – regulation of transcription, DNA-dependent – androgen receptor signaling pathway – interspecies interaction between organisms – response to DNA damage stimulus

K(lysine) Acetyltransferase 5 ist wie folgt lokalisiert:

chromatin – cytoplasm – cytosol – nucleus – protein complex – transcription factor complex – NuA4 histone acetyltransferase complex – Piccolo NuA4 histone acetyltransferase complex – histone acetyltransferase complex – nucleolus – perinuclear region of cytoplasm

Quelle: NCBI Entrez Gene, Gene Ontology