Die folgenden Gennamen und Gensymbole werden für Antigen K(lysine) Acetyltransferase 2B über verschiedene Spezies hinweg verwendet:

K(lysine) acetyltransferase 2B (KAT2B), K(lysine) acetyltransferase 2B (Kat2b), p300/CBP-associated factor (Pcaf), p300/CBP-associated factor (PCAF), K(lysine) acetyltransferase 2B (kat2b)

Zu den weiteren Synonymen zählen:

P, CAF, PCAF, P/CAF, Pcaf, p/CAF, AI461839, AW536563, A930006P13Rik, KAT2B, pcaf, MGC161980, zgc:161980, si:ch211-1j13.2

Auf Proteinebene tauchen folgende Bezeichner für Antigen K(lysine) Acetyltransferase 2B auf:

K(lysine) acetyltransferase 2B – CREBBP-associated factor – p300/CBP-associated factor – histone acetyltransferase KAT2B – histone acetylase PCAF – lysine acetyltransferase 2B – histone acetyltransferase PCAF

K(lysine) Acetyltransferase 2B erfüllt eine Reihe von Funktionen:

N-acetyltransferase activity – histone acetyltransferase activity – histone deacetylase binding – transcription coactivator activity – transferase activity – acyltransferase activity – cyclin-dependent protein kinase inhibitor activity – lysine N-acetyltransferase activity – protein binding – protein kinase binding – acetyltransferase activity – transcription factor binding

K(lysine) Acetyltransferase 2B spielt in den folgenden Prozessen eine Rolle:

N-terminal peptidyl-lysine acetylation – cell cycle – cell cycle arrest – chromatin remodeling – histone acetylation – interspecies interaction between organisms – metabolic process – negative regulation of cell proliferation – regulation of transcription, DNA-dependent – internal peptidyl-lysine acetylation – negative regulation of cyclin-dependent protein kinase activity – positive regulation of transcription – positive regulation of transcription from RNA polymerase II promoter – protein amino acid acetylation – regulation of transcription – transcription – cellular response to insulin stimulus

K(lysine) Acetyltransferase 2B ist wie folgt lokalisiert:

PCAF complex – chromatin remodeling complex – nucleoplasm – nucleus – A band – I band – actomyosin – histone acetyltransferase complex – kinetochore

Quelle: NCBI Entrez Gene, Gene Ontology